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Patients with Chronic Kidney Disease (CKD) frequently encounter potential inappropriate medications (PIMs) or Nephrotoxic drugs. Nevertheless, the influence of Nephrotoxic drugs on kidney outcomes in middle-aged patients remains insufficiently understood. The objective of this study was to shed light on the prescribing patterns of Nephrotoxic drugs for middle-aged individuals with CKD and their impact on the decline of kidney function. This study showed that patients with CKD who were prescribed
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