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FacebookBook Publisher International

$SOLVED:An isosteric series of compounds shown below, where \mathrm{X}=\mathrm{CH}_{2}, \mathrm{NH}, \mathrm{O}, \mathrm{S}, was synthesized. The order of potency was \mathrm{X}=\mathrm{NH}>\mathrm{O}>\mathrm{S}>\mathrm{CH}_{2}. How can you rationalize these results (you need to consider the threedimensional structure)?$

SOLVED:An isosteric series of compounds shown below, where \…

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