Safinamide Uses, Side Effects & Warnings - Drugs.com
WEBJul 10, 2024 · What is safinamide? Safinamide is monoamine oxidase inhibitor type B (MAO-B). safinamide works by allowing a chemical called dopamine (DOE pa meen) to …
Safinamide - Wikipedia
WEBSafinamide, sold under the brand name Xadago, is a medication used as treatment for Parkinson's disease with "off" episodes; it has multiple modes of action, including the inhibition of monoamine oxidase B. [4][5][7] It was approved in the European Union in February 2015, [4] in the United States in March 2017, [5] and in Canada in January …
Safinamide (Oral Route) Description and Brand Names - Mayo Clinic
WEBSafinamide is used in combination with levodopa and carbidopa to treat adults with Parkinson's disease who are having "off" episodes. This medicine is a MAO-B inhibitor that works to increase and extend the effects of levodopa and may help to slow the progress of Parkinson's disease.
Xadago (safinamide) - Uses, Side Effects, and More - WebMD
WEBJul 22, 2024 · Xadago (safinamide) is commonly used to treat Parkinson’s disease, a condition that affects the part of your brain that controls your movements. Xadago may also be used for other conditions as...
FDA approves drug to treat Parkinson’s disease - U.S. Food and …
WEBThe U.S. Food and Drug Administration today approved Xadago (safinamide) tablets as an add-on treatment for patients with Parkinson’s disease who are currently taking levodopa/carbidopa and...
Safinamide: Parkinson’s Uses, Side Effects, Warnings
WEBFeb 13, 2023 · Safinamide is a medication used in the treatment of Parkinson’s disease (PD), a movement disorder caused by the degeneration of nerve cells (neurons) in dopamine -producing regions of the brain.
The Current Evidence for the Use of Safinamide for the …
WEBJun 10, 2021 · Safinamide is one of the most recent approved drugs for fluctuating patients, in add-on to levodopa, that remains the gold standard treatment. It has a unique mechanism of action, both dopaminergic (as MAO-B inhibitor) and glutamatergic (through Na + channel blockade).
Safinamide: MedlinePlus Drug Information
WEBSafinamide is in a group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.
Safinamide: Uses, Interactions, Mechanism of Action - DrugBank …
WEBSafinamide is a unique molecule with multiple mechanisms of action and a very high therapeutic index. It combines potent, selective, and reversible inhibition of MAO-B with blockade of voltage-dependent Na+ and Ca2+ channels and inhibition of glutamate release.
Overall Efficacy and Safety of Safinamide in Parkinson’s Disease: A ...
WEBMar 5, 2021 · Safinamide is a potent, selective, yet reversible MAOB-I that also modulates Na + and Ca 2+ channels activity and reduces stimulated glutamate release, therefore acting on both the dopaminergic deficit and …