Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed.

An alternative strategy to replacing defective genes is ‘cytoreductive’ gene therapy, eradicating tumor cells directly (i.e. ‘suicide’ genes, induction of apoptosis) or indirectly (i.e. genes that elicit antitumor immune responses).

The meaning of induction and repression states that the former will induce and the latter will repress the gene expression in the presence of inducer and corepressor, respectively. The induction operon stimulates enzyme synthesis due to enough inducer molecules or substrates in the surrounding.

Apr 27, 2010 · Inducible gene expression has several features that distinguish it from the expression of genes that are constitutively active (for example, housekeeping genes). Inducible genes are highly...

Mar 29, 2010 · Here we develop a theoretical framework for a ligand-regulated gene-induction process that predicts the shape, position, and maximum activity of these dose–response curves. The theory is based on modeling the gene-induction process as an arbitrarily long sequence of complex-forming steps or reactions.

gene induction the activation of an inactive gene so that it can carry out TRANSCRIPTION. see OPERON MODEL.

Inducible gene regulation has been a critical tool in interrogating biological systems and designing synthetic circuits. Small-molecule induction enables temporal control and can be integrated into regulation at the levels of DNA, RNA, and protein activity.

The genes induced in response to extracellular signals fall into distinct transcription programs, each consisting of co-regulated and functionally related genes. Signal-dependent induction of one transcription program is usually accompanied by suppression …

Empowered by decades of development of inducible gene expression systems, researchers can now efficiently activate or suppress any gene, temporarily and quantitively at will, depending on experimental requirements and designs.

Nov 21, 2023 · When genes are turned on during gene expression, it is called gene induction, which is carried out by inducer or activator proteins. When genes are turned off during gene expression it is...