Caco-2 [Caco2] - HTB-37 - ATCC
WEBCaco-2 [Caco2] are epithelial cells isolated from colon tissue derived from a 72-year-old, White, male with colorectal adenocarcinoma. This cell line is a suitable transfection host and has applications in cancer and toxicology research.
Caco-2 Cell Line - PubMed
WEBThe Caco-2 cell line is originally derived from a colon carcinoma. However, one of its most advantageous properties is its ability to spontaneously differentiate into a monolayer of cells with many properties typical of absorptive enterocytes with brush border layer as found in the small intestine.
Caco-2 - an overview | ScienceDirect Topics
WEBCaco-2, a cell line obtained from human colon adenocarcinoma, is the most well-established intestinal cell model to date. Caco-2 cells differentiate into enterocyte-like cells after 21 days in culture and express a number of characteristic transporters [1,2].
Good Caco-2 cell culture practices - PubMed
WEBThe human Caco-2 cells differentiate spontaneously in culture forming monolayers of mature intestinal enterocytes which have been used as a model of the intestinal barrier for in vitro toxicology studies.
The Caco-2 Model: Modifications and enhancements to improve
WEBAug 25, 2022 · The Caco-2 cell model has been widely used to assess the permeability of drug candidates. It has provided a high throughput in vitro platform, functionally resembling the enterocytes.
Caco-2 Cell Line - SpringerLink
WEBThe human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its most advantageous properties is its ability to spontaneously...
Caco-2 | Cell - PubChem
WEBJan 5, 2022 · Cell information for Caco-2. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
The Caco-2 Model: Modifications and enhancements to improve …
WEBAug 25, 2022 · The Caco-2 monolayer allows the study of all major types of absorption pathways like the passive transcellular and paracellular diffusion, carrier mediated active and facilitated transport (influx and efflux).
Evaluation of Caco-2 and human intestinal epithelial cells as
WEBJul 18, 2022 · Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) compared to in vivo conditions. Therefore, we investigated Human Intestinal Epithelial Cells (HIECs) as an alternative in vitro model.
Caco-2 Cell Line Standardization with Pharmaceutical …
WEBOct 24, 2023 · The Caco-2 (Cancer coli-2) cell line is commonly used to assess the permeability of compounds in in vitro conditions. Caco-2 cells were isolated from colon tissue derived from a 72-year-old in the 1970s [ 12 ].
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