List of Azole antifungals - Drugs.com
Azole antifungals are a group of medicines that contain an azole ring and inhibit the growth of a wide range of fungi. They are classified into two groups: those with two nitrogens in the azole ring (the imidazoles; examples include clotrimazole, econazole, ketoconazole, miconazole, and tioconazole) and those with three nitrogens in the azole ...
Pharmacology of azoles - UpToDate
Jan 25, 2023 · INTRODUCTION. Azole antifungal agents have added greatly to the therapeutic options for treatment of systemic fungal infections. The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole).
Azole - Wikipedia
Skeletal formula of fluconazole - an antifungal medication. The search for antifungal agents with acceptable toxicity profiles led first to the discovery of ketoconazole, the first azole-based oral treatment of systemic fungal infections, in the early 1980s.
Current and Emerging Azole Antifungal Agents - PMC
The azole antifungal agents in clinical use contain either two or three nitrogens in the azole ring and are thereby classified as imidazoles (e.g., ketoconazole and miconazole, clotrimazole) or triazoles (e.g., itraconazole and fluconazole), respectively.
Antifungal Antibiotics - StatPearls - NCBI Bookshelf
Mar 7, 2023 · Azole drugs for local or topical use include powders, creams, ointments, gels, shampoos, and lozenges. Terbinafine, from the allylamine class of antifungals, can be administered topically or orally, which is dependent on the …
Fluconazole: Uses, Dosage, Side Effects, Warnings - Drugs.com
Jul 9, 2024 · Fluconazole is a prescription azole antifungal medication that may be used to treat serious fungal or yeast infections including those that affect the vagina, mouth or throat, lungs, bladder, or blood. It is available as an oral tablet, suspension, or injectable form.
Antifungal Ergosterol Synthesis Inhibitors - StatPearls - NCBI Bookshelf
Mar 1, 2024 · The primary mechanism of action involves the inhibition of ergosterol biosynthesis, leading to the disruption of fungal cell membrane integrity. Exploring these azole antifungal agents involves covering indications, contraindications, drug interactions, and adverse event profiles.
Azole Antifungals - DrugBank Online
An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. Econazole A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
Fluconazole: Uses, Interactions, Mechanism of Action - DrugBank …
Dec 31, 2015 · Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole.
Antifungal Medications: What You Should Know - Verywell Health
Mar 3, 2024 · Antifungal drugs are a class of medications that are used to treat invasive fungal infections. There is a wide range of types, strengths, formulations, and uses for the medications in this class. Each of these medications works by killing fungi-causing infection and/or stopping the fungi from continuing to grow.