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  1. Myc - Wikipedia

    • The Myc family was first established after discovery of homology between an oncogene carried by the Avian virus, Myelocytomatosis (v-myc; P10395) and a human gene over-expressed in various cancers, … See more

    Structure

    The protein product of Myc family genes all belong to the Myc family of transcription factors, which contain bHLH (basic helix-loop-helix) and LZ (leucine zipper) structural … See more

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    Function

    Myc proteins are transcription factors that activate expression of many pro-proliferative … See more

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    Myc-Nick

    Myc-nick is a cytoplasmic form of Myc produced by a partial proteolytic cleavage of full-length c-Myc and N-Myc. Myc cleavage is mediated by the calpainfamily of calcium-… See more

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    Clinical Significance

    A large body of evidence shows that Myc genes and proteins are highly relevant for treating tumors.Except for early response genes, Myc universally upregulates gene expression… See more

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  1. The MYC oncogene — the grand orchestrator of cancer growth

  2. MYC: a multipurpose oncogene with prognostic and therapeutic ...

  3. MYC Gene - GeneCards | MYC Protein | MYC Antibody

    Oct 2, 2024 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit. Among its related …

  4. Transcriptional regulation by MYC: an emerging new model

  5. MYC as a target for cancer treatment - PubMed

  6. MYC as a target for cancer treatment

  7. MYC function and regulation in physiological perspective

  8. MYC protein interactors in gene transcription and cancer

  9. The MYC oncogene - the grand orchestrator of cancer growth and …

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