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  1. Studies of gsh system
    PubMed
    The role of glutathione and glutathione peroxidase in regulating cellular level of reactive oxygen and nitrogen species
    Glutathione (GSH) and GSH/glutathione peroxidase (GPX) enzyme system is essential for normal intracellular homeostasis and gets disturbed under pathophysiologic conditions including endothelial dysfunction. Overproduction of reactive oxidative species (ROS) and reactive nitrogen species (RNS) includ...
    Author: Sheetal Panday
    Published: 2020/9
    Keywords: Antioxidant…
    ScienceDirect
    Review article The glutathione system in Parkinson’s disease and its progression
    Redox dysfunctions and neuro-oxidative stress play a major role in the pathophysiology and progression of Parkinson’s disease (PD). Glutathione (GSH) and the reduced/oxidized glutathione (GSH/GSSG) ratio are lowered in oxidative stress conditions and may lead to increased oxidative toxicity. GSH is ...
    Published: 2021/01/01
    Cited By: 0
    Keywords: DAQ dopa…
    PubMed
    The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes
    From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L-glutamyl-L-cysteinyl-glycine nucleophile tri-peptide, is the central player of this system that acts in redox homeostasis, d...
    Author: Corinne Cassi…
    Published: 2023/05/31
    Keywords: cyanobacte…
    National Center for Biotechnology Information
    Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis
    Cardiovascular diseases (CVDs) are the leading cause of death worldwide and rising health care costs [1]. Irreversible heart injury is the main culprit for the poor prognosis of CVDs. Therefore, understanding how cardiac tissue is impaired is critical to global health. Oxidative stress plays an esse...
    Author: Mingyue Tan, …
    Published: 2023/02
    Publication: Cell Deat…
    ScienceDirect
    Review Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging☆
    The tripeptide glutathione (GSH), namely γ-L-glutamyl-L-cysteinyl-glycine, is an ubiquitous low-molecular weight thiol nucleophile and reductant of utmost importance, representing the central redox agent of most aerobic organisms. GSH has vital functions involving also antioxidant protection, detoxi...
    Published: 2023/12/01
    Keywords: Aging; Glut…
    DOI: 10.1016/j.arr.2023…
  2. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    The glutathione system: a new drug target in neuroimmune …

    Tags:
    Reactive oxygen species
    Publish Year:2014
  3. Nature
    https://www.nature.com › articles

    Glutathione system enhancement for cardiac …

    Feb 16, 2023 · The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics...

  5. MDPI
    https://www.mdpi.com

    The Glutathione System: A Journey from Cyanobacteria to Higher …

    Tags:
    GSH System
    Cell
  6. Springer
    https://link.springer.com › article

    Glutathione and glutathione disulfide – their biomedical and ...

    Tags:
    Glutathione
    Antioxidant
  7. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    The role of glutathione and glutathione peroxidase in regulating ...

    Tags:
    GSH System
    Reactive oxygen species
    Publish Year:2020
  8. ScienceDirect
    https://www.sciencedirect.com › science › article › pii

    The glutathione system in Parkinson’s disease and its progression

    Tags:
    GSH System
    Reactive oxygen species
    Publish Year:2021
  9. Wikipedia
    https://en.wikipedia.org › wiki › Glutathi…

    Glutathione - Wikipedia

    Glutathione (GSH, / ˌɡluːtəˈθaɪoʊn /) is an organic compound with the chemical formula HOCOCH (NH2)CH2CH2CONHCH (CH2SH)CONHCH2COOH. It is an antioxidant in plants, animals, fungi, and some bacteria and archaea.

    Tags:
    Reactive Oxygen Species
    Glutamic Acid
    Glutathione-ascorbate Cycle
  10. Nature
    https://www.nature.com › articles

    Glutathione transferases: substrates, inihibitors and pro-drugs in ...

    Tags:
    Publish Year:2018
    Regulation of therapeutic goods
  11. Nature
    https://www.nature.com › articles

    Glutathione depletion induces ferroptosis, autophagy, and …

    Tags:
    Publish Year:2018
    Gpx4 Amd
    Gsh Depletion
    Glutathione Depletion
  12. Verywell Health
    https://www.verywellhealth.com

    Glutathione: Uses, Side Effects, and More - Verywell …

    Oct 5, 2024 · Glutathione (GSH), an antioxidant naturally produced by the liver and central nervous system, is purported to help metabolize toxins, break down free radicals, support immune function, and more.

    Tags:
    GSH System
    Side Effects