Open links in new tab
  1. Johns Hopkins Medicine
    https://www.hopkinsmedicine.org/health/conditions-and-diseases/igg-deficiencies

    IgG Deficiencies - Johns Hopkins Medicine

    • An IgG deficiency is a health problem in which your body doesn’t make enough Immunoglobulin G (IgG). People with IgG deficiency are more likely to get infections. When your body feels it is under attac… See more

    What Causes IgG Deficiencies?

    It’s not known what causes IgG deficiency. However, genetics may play a role. This condition is also thought to be linked to another immunoglobulin deficiency. See more

    Johns Hopkins Medicine
    What Are The Symptoms of An IgG Deficiency?

    Infections that most often affect people with IgG deficiency are: 1. Sinus infections and other respiratory infections 2. Gastrointestinal infections 3. Ear infections 4. Pneumo… See more

    Johns Hopkins Medicine
    How Is An IgG Deficiency Diagnosed?

    A blood test that measures immunoglobulin levels can diagnose IgG deficiency. It’s possible to have a normal level of total IgG, so the testing of the IgG subclasses is important. … See more

    Johns Hopkins Medicine
    How Is An IgG Deficiency Treated?

    Treatment depends on how bad your symptoms and infections are. When the symptoms come on later in life, the health problem is harder to manage. The person also tends t… See more

    Johns Hopkins Medicine
    How many IgG subclasses are there?
    There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). Subclasses IgG1, IgG2, IgG3, and IgG4 are differentiated on the basis of the size of the hinge region, position of interchain disulfide bonds, and molecular weight.
    microbenotes.com
    Feedback
    Table of Contents
    What Causes IgG Deficiencies?
    What Are The Symptoms of An IgG Deficiency?
    How Is An IgG Deficiency Diagnosed?
    How Is An IgG Deficiency Treated?
    How many IgG subclasses are there?
     
  1. There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). Subclasses IgG1, IgG2, IgG3, and IgG4 are differentiated on the basis of the size of the hinge region, position of interchain disulfide bonds, and molecular weight.

    Immunoglobulin G (IgG)- Structure, Subclasses and Functions …

    microbenotes.com/immunoglobulin-g-igg-structure-subclasses-and-functions/
    microbenotes.com/immunoglobulin-g-igg-structure-subclasses-and-functions/
    Was this helpful?
  2. People also ask
    What is IgG subclass deficiency?
    Individuals with IgG subclass deficiency are defined as having recurrent infections, persistently low levels of one or more IgG subclasses, and normal concentrations of total IgG, IgM, and IgA. IgG2 or IgG3 deficiencies are the most common IgG subclass deficiencies.

    IgG subclass deficiency | Immune Deficiency Foundation - Primary Imm…

    primaryimmune.org
    What is a normal IgG subclass?
    More details on IgG subclass deficiencies: The normal IgG breakdown in the bloodstream is: - 60-70% IgG1, - 20-30% IgG2, - 5-8% IgG3 - 1-3% IgG4

    IgG, Subclass 1 - Lab Results explained | HealthMatters.io

    healthmatters.io
    How many IgG subclasses are there?
    There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). Subclasses IgG1, IgG2, IgG3, and IgG4 are differentiated on the basis of the size of the hinge region, position of interchain disulfide bonds, and molecular weight.

    Immunoglobulin G (IgG)- Structure, Subclasses and Functions - Microb…

    microbenotes.com
    What is an example of an IgG subclass?
    For example, IgG1 and IgG3 subclasses are rich in antibodies against proteins such as the toxins produced by the diphtheria and tetanus bacteria, as well as antibodies against viral proteins.

    IgG, Subclass 1 - Lab Results explained | HealthMatters.io

    healthmatters.io
    Which IgG subclass is most important?
    The roughly 60-70% of total serum IgG that is the quantitatively most important IgG1 subclass contains important anti-protein antibodies. IgG1 deficiency generally results in hypogammaglobulinemia with increased susceptibility to bacterial infections. IgG2, which makes up roughly 20-30% of total serum IgG, contains important antipolysaccharide antibodies.

    IGG Subclass Booklet - Sanquin.org - for professionals

    sanquin.org
    What is the function of IgG subclasses?
    Each subclass serves predominantly (but not exclusively) a slightly different function in protecting the body against infection. For example, IgG1 and IgG3 subclasses protect against toxins from bacteria such as diphtheria and tetanus, and against viral infections.

    IgG subclass deficiency | Immune Deficiency Foundation - Primary Imm…

    primaryimmune.org
    Feedback
  3. Immune Deficiency Foundation
    https://primaryimmune.org/.../types-of-pi/igg-subclass-deficiency

    IgG subclass deficiency | Immune Deficiency Foundation - Primary …

  4. UpToDate
    https://www.uptodate.com/contents/igg-subclass-deficiency

    IgG subclass deficiency - UpToDate

  5. HealthMatters.io
    https://healthmatters.io/understand-blood-test-results/igg-subclass-1

    IgG, Subclass 1 - Lab Results explained | HealthMatters.io

  6. Labcorp
    https://www.labcorp.com/tests/209601

    209601: Immunoglobulin G, Subclasses (1-4) - Labcorp

  8. Mayo Clinic Laboratories
    https://www.mayocliniclabs.com/test-catalog/Overview/9259

    IGGS - Overview: IgG Subclasses, Serum - Mayo Clinic Laboratories

  9. Wikipedia
    https://en.wikipedia.org/wiki/IgG_deficiency

    IgG deficiency - Wikipedia

  10. Sanquin.org
    https://www.sanquin.org/.../iggsubclass-booklet.pdf
    [PDF]

    Human IgG Subclasses Useful Diagnostic Markers for

  11. frontiersin.org
    https://www.frontiersin.org/journals/immunology...

    Frontiers | IgG Subclasses and Allotypes: From Structure to ...

  12. Microbe Notes
    https://microbenotes.com/immunoglobu…

    Immunoglobulin G (IgG)- Structure, Subclasses and …

    Jun 24, 2022 · There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). Subclasses IgG1, IgG2, IgG3, and IgG4 are differentiated on the basis of the …