Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von …

Dec 25, 2024 · VWF (Von Willebrand Factor) is a Protein Coding gene. Diseases associated with VWF include Von Willebrand Disease, Type 1 and Von Willebrand Disease, Type 2 . Among …

Feb 20, 2023 · Von Willebrand factor (vWF) is a glycoprotein crucial to primary hemostasis through platelet and subendothelial collagen adhesion and the intrinsic coagulation cascade …

vWF在止血过程中主要由两种作用：①与 血小板 膜GPⅠb-Ⅸ复合物及内皮下胶原结合，介导血小板在 血管损伤 部位的黏附；②与因子Ⅷ结合，作为载体具有稳定因子Ⅷ的作用。此外，vWF …

Mar 26, 2015 · von Willebrand (VW) factor (VWF) is a multimeric glycoprotein present in blood plasma, the subendothelial matrix, as well as storage granules in endothelial cells (Weibel …

von Willebrand factor (VWF) is an adhesive and multimeric glycoprotein that found its historical origin in 1924, when the Finnish physician Erik von Willebrand first reported a family with a …

Von Willebrand factor, glycoprotein that plays an important role in stopping the escape of blood from vessels following vascular injury. Von Willebrand factor works by mediating the …

Oct 8, 2015 · von Willebrand factor (VWF) is a large multimeric glycoprotein that mediates the attachment of platelets to damaged endothelium and also serves as the carrier protein for …

Von Willebrand factor (vWF) is the largest protein found in plasma. It circulates in blood as a series of multimers ranging in size from 500 to 20,000 kDa. The variable molecular weight of …

Nov 21, 2024 · These structural adaptations provide VWF with the ability to regulate its interactions with a spectrum of ligands at the submolecular level to bind each ligand at the …