USF1 Gene - GeneCards | USF1 Protein | USF1 Antibody
Aug 6, 2024 · Complete information for USF1 gene (Protein Coding), Upstream Transcription Factor 1, including: function, proteins, disorders, pathways, orthologs, and expression.
USF1 modulates transcription and cellular functions by regulating ...
Oct 30, 2023 · Upstream transcription factor 1 (USF1) is a canonical transcription factor (TF) and is associated with the pathogenesis of several cancers, but its biological functions and molecular targets in HCC remain unclear.
Hematopoietic upstream stimulating factor 1 deficiency is ... - Nature
Aug 12, 2021 · Upstream stimulatory factor 1 (USF1) is a member of basic‐Helix–Loop–Helix–Leucine Zipper family of proteins that modulate the transcriptional activity of their target genes. USF1 was...
USF1 upstream transcription factor 1 [ (human)] - National Center …
A novel mutation in USF1 gene is associated with familial combined hyperlipidemia. Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen. The transcription factor USF1 promotes glioma cell invasion …
USF1-induced upregulation of LINC01048 promotes cell ... - Nature
Mechanistically, LINC01048 was proved to be transcriptionally activated by USF1. Pathway analysis and western blot assay showed that knockdown of LINC01048 led to the activation of Hippo pathway.
Upstream Transcription Factor 1 (USF1) allelic variants regulate ...
Apr 11, 2014 · We investigated sex-specific effects of USF1 gene allelic variants on serum indices of lipoprotein metabolism, early markers of asymptomatic atherosclerosis and their changes during six years of...
USF1/CD90 signaling in maintaining glioblastoma stem cells and …
Sep 1, 2022 · USF1 predicts a poor prognosis for glioma patients and is upregulated in patient-derived GSCs and glioblastoma cell lines. USF1 overexpression increases the proliferation, invasion, and neurosphere formation of GSCs and glioblastoma cell lines, while USF1 knockdown exerts an opposite effect.
Functional Variant Disrupts Insulin Induction of USF1:
Jun 12, 2009 · We observed that after a 2-hour insulin challenge, the dyslipidemia-associated allelic variant of USF1 had a significant effect on USF1 transcript levels in muscle. Only the nonrisk-allele homozygotes (AA) responded to the hyperinsulinemia with …
Genome-wide analyses in neuronal cells reveal that upstream
The upstream transcription factors (USFs) USF1 and USF2 are ubiquitously expressed transcription factors that are characterized by a conserved basic helix-loop-helix/leucine zipper DNA-binding domain. They form homo- or heterodimers, and recognize E-box motifs to modulate gene expression.
USF1 deficiency activates brown adipose tissue and improves ...
USF1 (upstream stimulatory factor 1) is a transcription factor associated with familial combined hyperlipidemia and coronary artery disease in humans. However, whether USF1 is beneficial or detrimental to cardiometabolic health has not been addressed.
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