Tropisetron - Wikipedia
Tropisetron is a serotonin 5-HT 3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.
Tropisetron: Uses, Interactions, Mechanism of Action - DrugBank …
Tropisetron is a 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. Tropisetron is an indole derivative with antiemetic activity.
Tropisetron: Nootropic Benefits, Uses, Dosage, & Side Effects
Jun 22, 2024 · Tropisetron is a potent medication that is commonly used to manage nausea and vomiting associated with chemotherapy or surgery. It’s often prescribed under the brand names Navoban or Setrovel. Interestingly, Tropisetron is also gaining interest for its nootropic benefits.
Tropisetron Mesylate - DrugBank Online
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Tropisetron: an update of its use in the prevention of ... - PubMed
Tropisetron is a serotonin (5-hydroxytryptamine; 5-HT) antagonist that is primarily used in the prevention of chemotherapy-induced nausea and vomiting. Antagonism of 5-HT3 binding sites in the peripheral and central nervous system is the probable mechanism of prevention of acute nausea and vomiting.
Pharmacology, toxicology and human pharmacokinetics of tropisetron …
Tropisetron is a novel, potent and highly selective 5-HT3 receptor antagonist, which is active in the treatment of nausea and vomiting induced by highly emetogenic chemothera-peutic drugs such as cisplatin.
Tropisetron | C17H20N2O2 | CID 656665 - PubChem
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Pharmacokinetics of therapeutic doses of tropisetron in healthy ...
Dec 12, 2000 · Tropisetron is a potent and selective 5-HT 3 receptor antagonist, and it is used primarily in the treatment of patients with chemotherapy-induced or postoperative nausea and vomiting. Tropisetron is almost completely absorbed from the gastrointestinal tract, but undergoes dose-dependent first pass metabolism.
Tropisetron Hydrochloride - DrugBank Online
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Definition of tropisetron - NCI Dictionary of Cancer Terms
Tropisetron blocks the action of the chemical serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. It is a type of serotonin receptor antagonist and a type of antiemetic.