TRIM33 Gene - GeneCards | TRI33 Protein | TRI33 Antibody
WEBAug 6, 2024 · TRIM33 (Tripartite Motif Containing 33) is a Protein Coding gene. Diseases associated with TRIM33 include Differentiated Thyroid Carcinoma and Epidermolysis Bullosa Simplex Generalized Type. Among its related pathways are Gene expression (Transcription) and Signaling by TGFB family members.
TRIM33 plays a critical role in regulating dendritic cell ...
WEBMay 31, 2024 · TRIM33 promoted the transcription of Irf8 to facilitate the differentiation of cDC1s by maintaining adequate CDK9 and Ser2 phosphorylated RNA polymerase II (S2 Pol II) levels at Irf8 gene...
Genome-wide screening identifies Trim33 as an essential ... - AAAS
WEBApr 12, 2024 · Trim33 -deficient mice displayed a near-complete loss of multiple DC subsets with minimal impact on monocytes or granulocytes. During DC differentiation, Trim33 repressed expression of type I interferon …
Tumour suppressor TRIM33 targets nuclear β-catenin degradation
WEBFeb 2, 2015 · In summary, our findings identify TRIM33 as a tumour suppressor that can abolish tumour cell proliferation and tumorigenesis by degrading nuclear β-catenin.
TRIM33 - an overview | ScienceDirect Topics
WEBTRIM33, also called TIF1γ, is the third member found in the TIF1 family. Like TRIM28, TRIM33 is also a multifunctional protein with many biological functions. It was initially …
The E3 ubiquitin ligase TRIM33 is essential for cytosolic RNA …
WEBOct 1, 2014 · TRIM33 binds to DHX33 directly and induces K63-linked ubiquitination. Since we found that TRIM33 is in a DHX33-interacting protein complex and TRIM33 is an E3 ubiquitin ligase, we next investigated whether DHX33 is the ubiquitination target of TRIM33.
TRIM33 tripartite motif containing 33 [ (human)] - National Center …
WEBJul 7, 2024 · TRIM33 prevents pulmonary fibrosis by impairing TGF-beta1 signalling. TRIM33 Overexpression Inhibits the Progression of Clear Cell Renal Cell Carcinoma In Vivo and In Vitro. Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells.
Trim33 masks a non-transcriptional function of E2f4 in ... - Nature
WEBAug 23, 2023 · We propose that the Trim33-E2f4-Recql axis controls progression of DNA replication forks along transcriptionally active chromatin to maintain genome integrity.
TRIM33 protein expression summary - The Human Protein Atlas
WEBActs as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquit in proteasome pathway. According to 1, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor.
The TRIM proteins in cancer: from expression to emerging regulatory ...
WEBOct 13, 2021 · TRIM3 is a tumor suppressor in GBM through asymmetric cell division restoration. TRIM3 loss during gliomagenesis raises the population of a glioma stem cell by disrupting the cell differentiation and asymmetric cell division [ …
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