Regulatory T cell - Wikipedia
WEBThe regulatory T cells ( Tregs / ˈtiːrɛɡ / or T reg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.
Regulatory T Cells Overview | Thermo Fisher Scientific - US
WEBRegulatory T cells (Treg) are critical to the maintenance of self-tolerance and immune cell homeostasis, which is demonstrated by the severe consequences of a lost or nonfunctional Treg population, as occurs in immune dysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX).
How regulatory T cells work | Nature Reviews Immunology
WEBRegulatory T (T Reg) cells are essential for maintaining peripheral tolerance, preventing autoimmunity and limiting chronic inflammatory diseases. However, they also limit beneficial...
Regulatory T cells (Tregs) and their therapeutic potential against ...
WEBMar 3, 2022 · This biological self–non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response regulators and play a pivotal role in …
Treg Heterogeneity, Function, and Homeostasis - PMC
WEBJan 14, 2020 · T-regulatory cells (Tregs) represent a unique subpopulation of helper T-cells by maintaining immune equilibrium using various mechanisms. The role of T-cell receptors (TCR) in providing homeostasis and activation of conventional T-cells is well-known; however, for Tregs, this area is understudied.
Regulatory T cells in autoimmune disease | Nature Immunology
WEBJun 20, 2018 · This Review summarizes the newer concepts of Treg cell instability, Treg cell plasticity and tissue-specific Treg cells, and their relationship to autoimmunity.
Principles of regulatory T cell function: Immunity
WEBFeb 14, 2023 · Treg cells are an immunosuppressive lymphocyte subset essential for preventing autoimmunity. Dikiy and Rudensky review the mechanisms by which Treg cells prevent autoimmunity, mitigate inflammation, and support tissue function.
FOXP3 + regulatory T cells and their functional regulation - Nature
WEBFeb 16, 2015 · Regulatory T (Treg) cells play a pivotal role in the maintenance of peripheral immunological tolerance and control of immune responses toward pathogens and tumors.
Regulatory T Cells: Concept, Classification, Phenotype, and
WEBRegulatory T cells (Treg) play an indispensable role in maintaining the body's immune nonresponse to self-antigens and suppressing the body's unwarranted and potentially harmful immune responses.
Regulatory T Cells: Mechanisms of Differentiation and Function
WEBRegulatory T (Treg) cell–mediated suppression serves as a vital mechanism of negative regulation of immune-mediated inflammation and features prominently in autoimmune and autoinflammatory disorders, allergy, acute and chronic …
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