Sep 17, 2018 · Transferrin is a crucial glycoprotein that shuttles iron in the blood. It would be an understatement to say that iron is vital for most life-sustaining processes. Transferrin has become an important biomarker for good health in the clinical setting, as it can reveal if a patient has functional iron depletion.

Jan 15, 2021 · Transferrin is a protein that binds iron and transports it throughout the body. It is the main iron carrier in the blood. When you have enough transferrin, your body can effectively use the iron you get from your diet [1, 2]. Transferrin levels increase with iron deficiency.

Apr 7, 2025 · Transferrin protein plays a critical role in maintaining iron balance in the body. Learn about its structure, function, and significance in iron transport and homeostasis.

Feb 15, 2005 · Transferrin, widely known as an iron-binding protein, is one such example of a multi-tasking protein. In this review, the multiple biological actions of transferrin, including its growth and cytoprotective activities, are discussed with the view of highlighting the potential therapeutic applications of this protein.

Transferrin, protein (beta1 globulin) in blood plasma that transports iron from the tissues and bloodstream to the bone marrow, where it is reused in the formation of hemoglobin. Found fixed to the surface of developing red blood cells, transferrin frees iron directly into the cell.

Transferrin (Tf) is a nonheme serum protein that binds with iron and helps in transporting it to the dividing cells. Transferrin binds with the transferrin receptor (Tfr) and gets internalized by the cells via endocytosis and finally dissociates the iron inside the acidic pH of the endosomes.

Jan 17, 2020 · The article by Tang et al. presents the novel observation that transferrin, an iron transport protein that exists in plasma in concentration excess to all the blood coagulation proteins,...

6 days ago · The transferrin receptor (TfR) is one of the key proteins involved in cellular iron uptake. TfR-mediated endocytosis of transferrin-bound iron is the major pathway for iron acquisition by most ...

Transferrin is a protein that is mainly produced by the liver. Its main function is to transport iron to the bone marrow, spleen, liver and muscles, which all play a role in various bodily function. The transferrin blood test is normally ordered to confirm and determine the type of anemia present.

Transferrin is an abundant serum metal-binding protein best known for its role in iron delivery. The human disease congenital atransferrinemia and animal models of this disease highlight the essential role of transferrin in erythropoiesis and iron metabolism.