Tocolytics (also called anti-contraction medications or labor suppressants) are medications used to suppress premature labor (from Greek τόκος tókos, "childbirth", and λύσις lúsis, "loosening").

Jan 18, 2024 · This is done through a procedure called tocolysis, in which medications from a specific category of drugs—known as tocolytics (toh-coh-LIT-iks)—are used to slow or stop contractions of uterine smooth muscle. Tocolytics may help delay labor by two to seven days.

Nov 5, 2020 · Tocolysis is an obstetrical procedure carried out with the use of medications with the purpose of delaying the delivery of a fetus in women presenting preterm contractions. These medications are administered with the hope of decreasing fetal morbidity and mortality.

Jun 17, 2002 · Treatment consists of bedrest, hydration, pharmacologic interventions, and combinations of these. We systematically reviewed the effectiveness of tocolytics to stop uterine contractions (first-line therapy) or maintain quiescence (maintenance therapy).

Sep 29, 2022 · In 2021, the Executive Guideline Steering Group (GSG) for the World Health Organization (WHO) maternal and perinatal health recommendations prioritized updating the then current recommendations on the use of tocolysis as published in the WHO recommendations on interventions to improve preterm birth outcomes.

This article seeks to apply this perspective to tocolytic therapy. Here, we provide a review of current tocolytic options and what the last decade of discovery has revealed about the regulation of myometrial excitability and quiescence.

Jul 11, 2024 · This topic will discuss the use of tocolytic medications for inhibition of acute preterm labor. Multiple other issues related to preterm labor, including pathogenesis, risk factors, clinical manifestations, evaluation, diagnosis, prevention, and neonatal outcome, are …

Tocolysis is the administration of therapeutic agents to prevent preterm birth. In the case of threatened preterm birth due to the premature onset of uterine contractions, tocolytic agents typically work through blocking the components of the signalling pathways that drive contractions in uterine myocytes, the smooth muscle cells of the uterus.

The decision as to which tocolytic agent should be used as first-line therapy for a patient is based on multiple factors, including gestational age, the patient’s medical history, common and severe side effects, and a patient’s response to therapy.

A tocolytic is a medication used to delay premature delivery by inducing uterine relaxation, thus improving fetal well-being or preparing for optimal delivery. AI generated definition based on: Pharmacology and Physiology for Anesthesia (Second Edition), 2019