TAF1 - Wikipedia
WEBTranscription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene.
TAF1 Gene - GeneCards | TAF1 Protein | TAF1 Antibody
WEBAug 6, 2024 · TAF1 is the largest component and core scaffold of the TFIID complex, involved in nucleating complex assembly (PubMed:25412659, 27007846, 33795473). TAF1 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF2 (PubMed:33795473).
TAF1, associated with intellectual disability in humans, is ...
WEBJul 24, 2019 · The TATA-box binding protein associated factor 1 (TAF1) protein is a key unit of the transcription factor II D complex that serves a vital function during transcription initiation. Variants of...
TAF1 gene - MedlinePlus
WEBThe TAF1 gene provides instructions for making part of a protein called transcription factor IID (TFIID). This protein is active in cells and tissues throughout the body, where it attaches (binds) to DNA. Transcription factor IID plays an essential role in regulating the activity of most genes.
TAF1, associated with intellectual disability in humans, is ...
WEBJul 24, 2019 · Here, we report clinical and genetic findings of a large family with a likely pathogenic variant in TAF1 and demonstrate TAF1’s association to neurogenesis by creating the first complete taf1 knockout model.
TAF1 TATA-box binding protein associated factor 1 [ (human)]
WEBTAF1 TATA-box binding protein associated factor 1 [ (human)] Gene ID: 6872, updated on 6-Jun-2024. Summary. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides.
Zinc knuckle of TAF1 is a DNA binding module critical for ...
WEBMar 15, 2018 · We show that the TAF1 zinc knuckle aids in the recruit of TFIID to endogenous promoters vital for cellular proliferation.
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