Synthetase Definition & Meaning - Merriam-Webster
WEBThe meaning of SYNTHETASE is an enzyme that catalyzes the linking together of two molecules usually using the energy derived from the concurrent splitting off of a pyrophosphate group from a triphosphate (such as ATP) —called also ligase.
Synthase - Wikipedia
WEBIn biochemistry, a synthase is an enzyme that catalyses a synthesis process. Note that, originally, biochemical nomenclature distinguished synthetases and synthases.
GMP Synthetase: Allostery, Structure, and Function - PMC
WEBSep 12, 2023 · Guanosine 5′-monophosphate (GMP) synthetase (GMPS, E.C. 6.3.5.2) catalyzes the final step in the de novo biosynthesis of GMP and belongs to the glutamine amidotransferase (GAT) family of enzymes.
Glutamine synthetase - Wikipedia
WEBGlutamine synthetase (GS) (EC 6.3.1.2) [3] is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH 3 → Glutamine + ADP + phosphate.
Aminoacyl-tRNA synthetases - PMC - National Center for …
WEBThe aminoacyl-tRNA synthetases are an essential and universally distributed family of enzymes that plays a critical role in protein synthesis, pairing tRNAs with their cognate amino acids for decoding mRNAs according to the genetic code.
Roles of aminoacyl-tRNA synthetases in immune regulation and
WEBNov 28, 2019 · Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized over the...
Aminoacyl tRNA synthetase - Wikipedia
WEBAn aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto its corresponding tRNA. It does so by catalyzing the transesterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA.
tRNA synthetase: tRNA Aminoacylation and beyond - PMC
WEBThe aminoacyl-tRNA synthetases (aaRSs) comprise an ancient family of enzymes that are responsible for the first step of protein synthesis. This diverse set of proteins is united by a common aminoacylation reaction, which attaches an amino acid to its cognate tRNA.
Synthetase - an overview | ScienceDirect Topics
WEBSynthetase refers to a family of enzymes that play a crucial role in various cellular processes. In the context of disease, the most common involvement of synthetases is seen in 'anti-synthetase syndrome', where individuals develop antibodies against specific synthetases, leading to symptoms like muscle inflammation, interstitial lung disease ...
tRNA synthetase: tRNA aminoacylation and beyond - Pang
WEBApr 4, 2014 · The aminoacyl-tRNA synthetases are prominently known for their classic function in the first step of protein synthesis, where they bear the responsibility of setting the genetic code. Each enzyme is exquisitely adapted to covalently link a single standard amino acid to its cognate set of tRNA isoacceptors.
- Some results have been removed