Open links in new tab

  1. Sjögren's syndrome - Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Sjögren's syndrome is diagnosed based on symptoms and certain tests.

    Common tests & procedures

    Schirmer's test: For testing tear production rate.

    Saliva flow test: For salivary gland test.

    Blood test: For checking levels of antinuclear antibodies. Low blood count, erythrocyte sedimentation rates are also other markers.

    See more

    Treatment

    Verified Expert

    Currently there is no cure for Sjögren's syndrome, treatment can improve the various symptoms and prevent complications.

    Medication

    Salivary stimulants: Drugs used to increase the production of saliva.

    Pilocarpine . Cevimeline

    Nonsteroidal anti-inflammatory drugs (NSAIDs): Used to treat wide range symptoms associated with the disease.

    Hydroxychloroquine

    See more

    Specialist

    Verified Expert

    Ophthalmologist : Specializes in the medical and surgical care of the eyes.

    Rheumatologist : Specializes in the treatment of arthritis, autoimmune diseases, pain disorders affecting joints, and osteoporosis.

    Otolaryngologist : Specializes in the diagnosis and treatment of diseases of the ear, nose and throat.

    See more
    Does Sjögren's syndrome have autoantibodies?
    About 50% of patients with Sjögren’s syndrome have autoantibodies in their blood. The presence of antibodies can help differentiate primary Sjögren’s syndrome from secondary Sjögren’s syndrome (which occurs secondary to another autoimmune condition). Anti-SS-A antibodies are more common than anti-SS-B antibodies.
    verywellhealth.com

    Complications

    Verified Expert

    Sjögren's syndrome if left untreated can lead to the following complications:

    • Eye problems – Corneal ulcers, sensitive to light and blurred vision
    • Dental cavities – Lack of saliva production can lead to bacterial infection in teeth and leads to cavity formation
    • Infection – High risk of Yeast Infection for people with Sjögren's syndrome

    Other Problems include:

    • Lungs, kidneys or liver problems – Inflammation can lead to infection in lungs, kidneys and liver
    • Pregnancy problems

    See more

    Get credible answers from verified health professionals

    Post anonymouslyAsk Health Experts Navigation chevron
    Microsoft Start Health
    Diagnosis - Sjögren’s Foundation
    Sjögren’s Foundation
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice.
    Feedback
    Table of Contents
    Diagnosis
    Treatment
    Specialist
    Does Sjögren's syndrome have autoantibodies?
    Complications
    Ask an expert
     
  1. Sjögren’s antibodies include anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). These antibody levels can be measured in the blood. Anti-SS-A and anti-SS-B are considered autoantibodies. They contribute to disease by attacking the body’s own tissue.

    Sjogren’s Antibodies: Uses, Procedure, Results - Verywell Health

    www.verywellhealth.com/sjogrens-antibodies-5105025
    www.verywellhealth.com/sjogrens-antibodies-5105025
    Was this helpful?
  2. People also ask
    Which antibodies are associated with Sjögren's syndrome?
    Anti-SS-A and anti-SS-B are autoantibodies that are associated with Sjögren’s syndrome. Anti-SSA and anti-SSB antibodies attack healthy glands that produce tears and saliva and can be present in several autoimmune conditions.

    Sjogren’s Antibodies: Uses, Procedure, Results - Verywell Health

    verywellhealth.com
    How prevalent is Sjogren’s syndrome?

    Dr. Ilya Aleksandrovskiy

    M.D., MBA · 5 years of exp

    1 in 400 people gets Sjogren's syndrome. Sjogren's syndrome is one of the top three most common systemic autoimmune diseases.
    +4 more answers
    bing.com
    Does Sjögren's syndrome have autoantibodies?
    About 50% of patients with Sjögren’s syndrome have autoantibodies in their blood. The presence of antibodies can help differentiate primary Sjögren’s syndrome from secondary Sjögren’s syndrome (which occurs secondary to another autoimmune condition). Anti-SS-A antibodies are more common than anti-SS-B antibodies.

    Sjogren’s Antibodies: Uses, Procedure, Results - Verywell Health

    verywellhealth.com
    Can antibodies help diagnose Sjögren's disease?
    While the presence of these antibodies can help doctors diagnose Sjögren’s disease, this alone cannot diagnose the disorder because these antibodies may be present in healthy individuals and people with other disorders as well.

    Sjögren’s Disease: Diagnosis, Treatment, and Steps to Take

    niams.nih.gov
    Are SS-B antibodies common in Sjögren's disease?
    SS-A antibodies are found in approximately 60-80% of Sjögren’s disease patients. SS-B antibodies are less common, being found in approximately 30-50% of Sjögren’s disease patients. SS-A antibodies thus occur commonly by themselves. However, it is very uncommon for SS-B antibodies to occur alone.

    Blood and Urine Tests : Johns Hopkins Sjögren’s Center

    hopkinssjogrens.org
    What do elevated Sjögren's antibodies indicate?
    Elevated Sjögren’s antibodies—anti-SS-A and anti-SS-B—are suggestive of inflammatory connective tissue disease. Elevated results on this test may indicate Sjögren’s syndrome or another autoimmune disease such as lupus or rheumatoid arthritis.

    Sjogren’s Antibodies: Uses, Procedure, Results - Verywell Health

    verywellhealth.com
    Feedback
  3. Mayo Clinic
    https://www.mayoclinic.org › diseases-conditions › ...

    Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic

  4. Johns Hopkins Sjögren’s Center
    https://www.hopkinssjogrens.org › disease...

    Blood and Urine Tests : Johns Hopkins Sjögren’s Center

  5. Sjögren’s Foundation
    https://sjogrens.org › understanding-sjo…

    Diagnosis - Sjögren’s Foundation

    SS-A (or Ro) and SS-B (or La): Marker antibodies for Sjögren’s. 70% of Sjögren’s patients are positive for SS-A and 40% are positive for SS-B. Also found in lupus patients. Eye Tests. Schirmer test: Measures tear production. Rose Bengal …

  6. Johns Hopkins Sjögren’s Center
    https://www.hopkinssjogrens.org › disease...

    Diagnosis of Sjögren's Disease - Johns Hopkins Sjögren’s Center

  7. UpToDate
    https://www.uptodate.com › contents › diagnosis-and...

    Diagnosis and classification of Sjögren's disease - UpToDate

  8. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Autoantibodies in Sjögren's syndrome and its classification criteria

  9. nih.gov
    https://www.niams.nih.gov › health-topics › sjogrens...

    Sjögren’s Disease: Diagnosis, Treatment, and Steps to Take

  10. Mayo Clinic
    https://www.mayoclinic.org › diseases-conditions › ...

    Sjogren's syndrome - Symptoms and causes - Mayo Clinic

  11. Johns Hopkins Medicine
    https://www.hopkinsmedicine.org › health › conditions...

    Sjögren's Syndrome Diagnosis - Johns Hopkins Medicine