Schiff base - Wikipedia
Schiff bases are common enzymatic intermediates where an amine, such as the terminal group of a lysine residue, reversibly reacts with an aldehyde or ketone of a cofactor or substrate. The common enzyme cofactor pyridoxal phosphate (PLP) forms a Schiff base with a lysine residue and is transaldiminated to the substrate (s). [7]
Reaction with Primary Amines to form Imines - Chemistry …
Jan 23, 2023 · The reaction of aldehydes and ketones with ammonia or 1º-amines forms imine derivatives, also known as Schiff bases (compounds having a C=N function). Water is eliminated in the reaction, which is acid-catalyzed and reversible in the same sense as acetal formation.
Schiff Bases: Contemporary Synthesis, Properties, and Applications
Jun 3, 2024 · Efficient formation of Schiff bases, a pivotal process in organic synthesis, relies on judicious selection of catalysts and reaction conditions. Traditional methods often involve metal catalysts, but contemporary approaches prioritize eco-friendly alternatives to mitigate environmental impact.
Overview of Schiff Bases - IntechOpen
Oct 19, 2022 · Schiff base formation reaction. The structures of Schiff bases are determined by the tautomeric transformations that occur depending on the polarity of the solvent and the hydrogen bonds that occur in the molecule.
21.4: Imine formation - Chemistry LibreTexts
The reaction of aldehydes and ketones with ammonia or 1º-amines forms imine derivatives, also known as Schiff bases (compounds having a C=N function). Water is eliminated in the reaction, which is acid-catalyzed and reversible in the same sense as acetal formation.
Schiff Base - Structure, Synthesis, and Biological Applications
Schiff’s bases are formed when any primary amine reacts with an aldehyde or a ketone under specific conditions. In other words, it is a nitrogen analogue of a ketone or aldehyde where the carbonyl group has been replaced by an azomethine or imine group.
Schiff Base - an overview | ScienceDirect Topics
A Schiff base is a compound formed by condensing a carbonyl-containing aldehyde or ketone with a nitrogen-based counterpart, resulting in the replacement of the carbonyl group with an imine group called azomethine.
Schiff bases and their metal Complexes: A review on the history ...
Apr 1, 2023 · Metallic complexation obtained from Schiff base ligands is generally synthesized by combining the Schiff base with readily available metallic complexes, including metal amides, alkyls, acetates, or halides.
Schiff Base - an overview | ScienceDirect Topics
Schiff Base Formation. Aquated acids or bases can hydrolyze Schiff bases back to their respective reactants. Nucleophilic addition to the carbonyl group is also involved in the mechanism of Schiff base formation, where the amine is involved as the nucleophile.
19.9: Nucelophilic Addition of Amines (Imine and Enamine Formation)
The reaction of aldehydes and ketones with ammonia or 1º-amines forms imine derivatives, also known as Schiff bases (compounds having a C=N function). Water is eliminated in the reaction, which is acid-catalyzed and reversible in the same sense as acetal formation.