Ubiquinol - Wikipedia
A ubiquinol is an electron-rich (reduced) form of coenzyme Q (ubiquinone). The term most often refers to ubiquinol-10, with a 10-unit tail most commonly found in humans. The natural ubiquinol form of coenzyme Q is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals.
Q cycle - Wikipedia
The Q cycle (named for quinol) describes a series of sequential oxidation and reduction of the lipophilic electron carrier Coenzyme Q (CoQ) between the ubiquinol and ubiquinone forms.
Coenzyme Q – cytochrome c reductase - Wikipedia
The coenzyme Q : cytochrome c – oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain (EC 1.10.2.2), playing a critical role in biochemical generation of ATP (oxidative phosphorylation).
Coenzyme Q biochemistry and biosynthesis - Cell Press
Jan 24, 2023 · Coenzyme Q (CoQ) is a remarkably hydrophobic, redox-active lipid that empowers diverse cellular processes. Although most known for shuttling electrons between mitochondrial electron transport chain (ETC) complexes, the roles for …
Q Cycle in Electron Transport Chain | EasyBiologyClass
Q Cycle Explained: Discover the critical role of the Q cycle in electron transport chain. Learn how Coenzyme Q's oxidation and reduction facilitate proton movement across the mitochondrial membrane, driving cellular respiration.
Mitochondria regulate intracellular coenzyme Q transport and ...
Jan 19, 2023 · Coenzyme Q (or ubiquinone) is a redox-active lipid that serves as universal electron carrier in the mitochondrial respiratory chain and antioxidant in the plasma membrane limiting lipid...
Ubiquinone - an overview | ScienceDirect Topics
Jan 3, 1999 · At the cytosolic face the reduced form, ubisemiquinone (QH2), is oxidized by complex III to its semiquinone by transferring an electron via an Fe-S cluster to cytochrome c1, and then to Q10 by transferring another electron via b566 to b560.
Endogenous and exogenous regulation of redox-properties of …
Ubiquinol (QH2, reduced coenzyme Q) is increasingly reported to exert antioxidant functions besides its implication in mitochondrial energy metabolism. On the other hand ubisemiquinones (SQ-.) of the respiratory chain are considered to account for the production of superoxide radicals as a byproduct …
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain
Apr 5, 2016 · A shift from glucose to fatty acids increases electron flux through FAD, which can saturate the oxidation capacity of the dedicated coenzyme Q (CoQ) pool and result in the generation of reactive oxygen species.
Antioxidant-derived prooxidant formation from ubiquinol
Ubiquinol (QH2) is increasingly used as antioxidant for the treatment of a variety of diseases and the modulation of biological aging; however, the biological significance of secondary reaction products has been disregarded so far.