Prince Charles Hospital is a district general hospital in Gurnos, Merthyr Tydfil, Wales. It is managed by the Cwm Taf Morgannwg University Health Board. Construction of the first phase of the new hospital began in 1972 and it was officially opened in 1978. Services were transferred from Merthyr General Hospital in 1986, and once a second phase of the Prince Charles Hospital had been completed in 1991, services also transferred from Buckland Hospital.