Podocyte - Wikipedia
Podocytes are cells in Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus. Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. [1]
Podocytes - PMC - National Center for Biotechnology Information
Jan 28, 2016 · Podocytes (or visceral epithelial cells) are terminally differentiated cells lining the outer surface of the glomerular capillaries.
Podocytes - PubMed
Jan 28, 2016 · Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration, podocytes play an active role in preventing plasma proteins from entering the urinary ultrafiltrate by providing a bar ….
Podocyte-targeted therapies — progress and future directions
May 9, 2024 · Podocytes are the key target cells for injury across the spectrum of primary and secondary proteinuric kidney disorders, which account for up to 90% of cases of kidney failure worldwide.
Cell Biology and Pathology of Podocytes - PMC - National Center …
Podocytes are pericyte-like cells with a complex cellular organization consisting of a cell body, major processes, and foot processes (FPs).
Podocyte | Complete Anatomy - Elsevier
A podocyte is a modified epithelial cell of the visceral layer of the glomerular capsule in the renal glomerulus; it has a small perikaryon and several primary and secondary foot-like radiating processes (pedicels) that interdigitate with those of other podocytes and embrace the walls of glomerular capillaries (Dorland, 2011).
Role of biophysics and mechanobiology in podocyte physiology
Mar 5, 2024 · Key points. Podocytes are crucial for maintaining glomerular filtration and must have enough biophysical resilience to adapt to (or balance) mechanical forces in their environment. Loss of ...
Podocyte Biology and Pathogenesis of Kidney Disease - PMC
Podocytes are terminally differentiated cells of the kidney glomerulus that are essential for the integrity of the kidney filter. Their function is primarily based on their intricate structure, which includes foot processes.
Podocyte–actin dynamics in health and disease - Nature
Aug 30, 2016 · In this Review we provide a comprehensive overview of the physiologic role of podocytes in the architectural and functional properties of the glomerular filtration barrier, emphasizing the role...
Podocyte - an overview | ScienceDirect Topics
The podocyte, also known as the glomerular visceral epithelial cell, is a highly differentiated cell that plays a crucial role in maintaining the structure and function of the glomerular filtration barrier in the kidney.