Pneumocytes
Learn about the two types of pneumocytes, the surface epithelial cells of the alveoli, and their functions in gas exchange and surfactant production. Explore the effects of capillary leakage and neutrophil accumulation on the alveoli.
Pulmonary alveolus - Wikipedia
Learn about the structure, function, and development of pulmonary alveoli, the tiny air sacs in the lungs where gas exchange takes place. Find out how alveoli are affected by diseases, surfactant, inflammation, and coronavirus.
Histology, Alveolar Cells - StatPearls - NCBI Bookshelf
Aug 28, 2023 · The cytoplasm within the leaflets contains cytoskeletal fibrils, microtubules, and membrane vesicles for transcellular transport. The fused basal laminae of the type I pneumocyte and the capillary endothelial cell can be appreciated when observed under EM. Type II cells are large and cuboidal.
Alveoli: Anatomy, function and clinical points | Kenhub
Oct 30, 2023 · Learn about the structure and function of the pulmonary alveoli, the small air sacs that facilitate gas exchange in the lungs. Find out how alveolar cells, surfactant, and macrophages contribute to respiration and how they are affected by diseases.
Pneumocyte - an overview | ScienceDirect Topics
Learn about pneumocytes, the cells that line the alveoli of the lungs and enable gas exchange. Find chapters and articles on pneumocyte development, function, and diseases from various scientific sources.
Pneumocyte - an overview | ScienceDirect Topics
Feb 7, 2011 · Learn about pneumocytes, the cells that line the alveoli of the lungs and participate in gas exchange and surfactant production. Find out how Ndst1 deficiency affects pneumocyte differentiation, surfactant secretion, and BMP signaling in the developing lung.
Alveolar type 2 progenitor cells for lung injury repair
Feb 8, 2019 · The healthy human lung comprises of the cuboidal AT2 pneumocyte (15%) of total cells 20. The surfactant protein (SP) C-expressing embryologic precursor is majorly found in AT2 cell 21.
Isolation and characterisation of alveolar type II pneumocytes …
Aug 9, 2018 · Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.
Type 2 alveolar cells are stem cells in adult lung - PubMed
Gas exchange in the lung occurs within alveoli, air-filled sacs composed of type 2 and type 1 epithelial cells (AEC2s and AEC1s), capillaries, and various resident mesenchymal cells. Here, we use a combination of in vivo clonal lineage analysis, different injury/repair systems, and in …
Human Lung Stem Cell-Based Alveolospheres Provide Insights …
Alveolospheres are 3D cultures of human alveolar type 2 cells that can be infected with SARS-CoV-2 and show features of COVID-19 lungs. This article describes the generation, characterization, and application of alveolospheres for studying SARS-CoV-2-mediated interferon responses and pneumocyte dysfunction.
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