Phosphatidylcholine levels may decrease as we age. For example, in the brain, there is a 10% reduction between age 40 and age 100. Uses: Can be used to level out elevated cortisol levels. Histamine N-methyltransferase (HMT) can be stimulated by Phosphatidylcholine. Used to treat brain and liver disease as well as atherosclerosis.

We have established that phosphatidylserine as a supplement may help reduce cortisol levels in the body, something many sportsmen want to build up muscle. However, it may also play a significant role in bringing down cortisol levels during the initial stages of adrenal fatigue when cortisol levels are at their highest.

Phosphatidyl choline is an essential chemical when it comes to brain cell reproduction, and can help improve focus, as well as concentration. PC has effects that possibly enable it to pacify the inflammation and metabolic stress response circuits of the NEM stress response.

May 28, 1980 · Exposure of the cells to a combination of cortisol and thyroxine caused increases in the rates of synthesis of total and disaturated phosphatidylcholines from labelled choline, palmitate, and glycerol and in that of phosphatidyl-glycerols from labelled glycerol. These increases were about the same as those brought about by cortisol alone.

PS supplementation promotes a desired hormonal status for athletes by blunting increases in cortisol levels. Phosphatidylserine (PS) is a naturally occurring phospholipid nutrient that is most concentrated in organs with high metabolic activity, such as the brain, lungs, heart, liver, and skeletal muscle.

May 28, 1980 · Exposure of the cells to a combination of cortisol and thyroxine caused increases in the rates of synthesis of total and disaturated phosphatidylcholines from labelled choline, palmitate, and glycerol and in that of phosphatidylglycerols from labelled glycerol. These increases were about the same as those brought about by cortisol alone.

Phosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15 % of the phospholipids in the human cerebral cortex [1]. In the plasma membrane, PS is localized exclusively in the cytoplasmic leaflet where it forms part of protein docking sites necessary for the activation of several key signaling pathways.

Fortunately, scientists have discovered that phosphatidylserine, DHEA, and ginkgo biloba can reduce cortisol levels, helping to keep this catabolic hormone from damaging your body. Cortisol is one of several hormones in the hypothalamic-pituitary-adrenal axis.

In this review, we discuss the metabolism of PS, the anti-inflammation function of PS in the brain; the alterations of PS in different CNS diseases, and the possibility of PS to serve as a therapeutic agent for diseases. Clinical studies have showed that PS has no side effects and is well tolerated.

Mar 6, 2017 · Phosphatidylcholine (PC), often formed from the metabolism of lecithin (which also contains linoleic and linolenic acids) and is an integral component of this methylation process. What is Phosphatidylcholine and why is it so important? PC is a major component of cellular membranes and is the most abundant phospholipid in the body.