Open links in new tab
  1. Piperidine
    PiperidineChemical compound
    Chemical structureUsesFunctionMolar massSolubilityCommon namePropertiesHazards
     
  2. Wikipedia
    https://en.wikipedia.org/wiki/Piperidine

    Piperidine - Wikipedia

    • Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). It is a colorless liquid with an odor described as objectionable, typical of amines. The name comes from the genus name Piper, which is the Latin word for pe… See more

    Production

    Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by … See more

    Natural occurrence of piperidine and derivatives

    Piperidine itself has been obtained from black pepper, from Psilocaulon absimile (Aizoaceae), and in Petrosimonia monandra.
    The piperidine structural motif is present in numerous … See more

    See more images of Piperidine
    See more images of Piperidine
    All images
    CAS Number110-89-4
    3D model (JSmol)Interactive image
    ChEBICHEBI:18049
    ChEMBLChEMBL15487
    Conformation

    Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial … See more

    Reactions

    Piperidine is widely used to convert ketones to enamines. Enamines derived from piperidine are substrates in the Stork enamine alkylation reaction.
    Upon treatment with calcium hypochlorite, piperidine c… See more

    NMR chemical control

    • C NMR: (CDCl3, ppm) 47, 27.2, 25.2
    • H NMR: (CDCl3, ppm) 2.79, 2.19, 1.51 See more

    Uses

    Piperidine is used as a solvent and as a base. The same is true for certain derivatives: N-formylpiperidine is a polar aprotic solvent with better hydrocarbon solubility than other amide solvents, and 2,2,6,6 … See more

    List of piperidine medications

    Piperidine and its derivatives are ubiquitous building blocks in pharmaceuticals and fine chemicals. The piperidine structure is found in, for example:
    • Icaridin (Insect repellent)
    • SSRIs (selective serotonin r… See more

    Wikipedia text under CC-BY-SA license
    Feedback
    Table of Contents
    Production
    Natural occurrence of piperidine and derivatives
    Quick Facts
    Conformation
    Reactions
    NMR chemical control
    Uses
     
  1. PubChem
    https://pubchem.ncbi.nlm.nih.gov/compoun…

    Piperidine | C5H11N | CID 8082 - PubChem

    Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.

  3. Material Properties
    https://material-properties.org/piperidine

    Piperidine | Formula, Properties & Application

  4. ScienceDirect
    https://www.sciencedirect.com/topics/neuroscience/piperidine

    Piperidine - an overview | ScienceDirect Topics

  5. ScienceDirect
    https://www.sciencedirect.com/topics/chemistry/piperidine

    Piperidine - an overview | ScienceDirect Topics

  6. Explore Pepridine

  7. NIST Chemistry WebBook
    https://webbook.nist.gov/cgi/cbook.cgi?ID=C110894&Mask=1EFF

    Piperidine - NIST Chemistry WebBook

  8. ScienceDirect
    https://www.sciencedirect.com/topics/pharmacology...

    Piperidine - an overview | ScienceDirect Topics

  9. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/product/sial/104094

    Piperidine ReagentPlus , 99 110-89-4 - MilliporeSigma

  10. NIST Chemistry WebBook
    https://webbook.nist.gov/cgi/cbook.cgi?ID=C110894&Type=TBOIL

    Piperidine - NIST Chemistry WebBook

  11. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/product/aldrich/411027

    Piperidine = 99.5 , redistillation 110-89-4 - MilliporeSigma