Sarcoidosis can also affect extraocular muscles, orbital fat and the optic nerve sheath and can present with palpable masses, eyelid swelling, ptosis, proptosis and pain. These manifestations resemble other orbital inflammatory conditions like thyroid ophthalmopathy, which can occur simultaneously with ocular sarcoidosis [9] .

Nov 3, 2022 · Orbital manifestations of sarcoidosis are common among patients with systemic sarcoidosis and can involve the lacrimal gland, the orbit, soft tissues of the orbit, and the optic nerve. Uveitis is by far the most common manifestation and is typically bilateral 5.

We present a series of biopsy-proven orbital and adnexal sarcoidosis, including treatment details and outcomes. Our study highlights the clinical features of extralacrimal orbital sarcoidosis, an uncommon condition that may be the initial feature of systemic sarcoidosis.

Aug 25, 2023 · Ocular sarcoidosis is an inflammatory condition that can involve any part of the eye leading to conjunctival granuloma, episcleritis/scleritis, uveitis, optic neuropathy, and/ or its adnexal tissues leading to lacrimal gland enlargement and orbital inflammation.

We report two cases of presumed orbital sarcoidosis involving multiple extraocular muscles that were initially diagnosed as thyroid eye disease but were later reclassified as orbital sarcoidosis after orbital biopsies showed noncaseating granulomatous inflammation in the absence of systemic disease.

The management of orbital and adnexal sarcoidosis varies based on the tissue involved, extent of the disease, and presence of associated systemic involvement. Treatment options include observation, oral corticosteroids, surgical debulking, complete excision, and systemic immunosuppressants.

Orbital and adnexal sarcoidosis usually presents as enlargement of the lacrimal gland(s), but also can present as a diffuse, solid mass with irregular infiltration of orbital structures, extraocular muscles, or lacrimal sac.

Objective: To present the clinical features and management in a series of patients with orbital and adnexal sarcoidosis. Methods: This multicenter retrospective study included patients with biopsy-proven noncaseating granuloma involving the orbit or …

Dec 17, 2017 · Orbital sarcoidosis is a chronic multisystem granulomatous disease involving all organ systems. In case of systemic involvement, clinical manifestations of sarcoidosis occur in the CNS in 10% of cases (Mafee and Dorodi 1999 ).

Unexplained chronic eyelid swelling without a mass should be considered a possible ophthalmic manifestation of orbital sarcoidosis. Keywords: Chronic swelling, Lower lid, Orbital sarcoidosis. Sarcoidosis is a multisystem granulomatous disorder of unknown etiology.