- Studies of Obese Mice
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See all on Wikipediaob/ob mouse - Wikipedia
The ob/ob or obese mouse is a mutant mouse that eats excessively due to mutations in the gene responsible for the production of leptin and becomes profoundly obese. It is an animal model of type II diabetes. Identification of the gene mutated in ob led to the discovery of the hormone leptin, which is important in the … See more
Wikipedia text under CC-BY-SA license Diet-induced obesity in animal models: points to consider and …
See more on dmsjournal.biomedcentral.comInitially, 90474 articles were found: 70658 by using the terms “diet” + “obesity” and 19816 by the terms “high fat diet” + “obesity”. After using the filters on PubMed database, 1625 articles were found for the “diet” + “obesity” search and 819 articles for the “high fat diet” + “obesity” search, totaling 2444 articles. After the exclusion …- Author: Mariana de Moura E Dias, Sandra Aparecida Dos Reis, Lisiane Lopes da Conceição, Catarina Maria Nogue...
- Published: Mar 18, 2021
- Publish Year: 2021
C57BL/6J substrain differences in response to high-fat diet ...
Aug 20, 2020 · C57BL/6J-related mouse strains are widely used animal models for diet-induced obesity (DIO). Multiple vendors breed C57BL/6J-related substrains which may introduce …
Effects of different diets used in diet-induced obesity models on ...
Dec 20, 2019 · In conclusions, CAF and HFD are both reliable mouse diets in inducing visceral obesity, glucose intolerance and insulin resistance. CAF is more effective than HFD in causing …
Obesity causes mitochondrial fragmentation and dysfunction in …
Jan 29, 2024 · Mitochondrial dysfunction is a characteristic trait of human and rodent obesity, insulin resistance and fatty liver disease. Here we show that high-fat diet (HFD) feeding …
A systematic review on different models of inducing obesity in …
The studies have revealed that mice can attain a weight three times more than unaffected mice. It was found that the obese mice had enlargement of the pancreas and increased production of …
From Leptin to Lasers: The Past and Present of Mouse Models of …
The use of obese mouse models provides unique insight into the hormones and mechanisms that regulate appetite and metabolism. Paramount among these models are the “obese” and …
Obesity genetics in mouse and human: back and forth, and back …
Mar 24, 2015 · Mouse models are the most common experimental animals in obesity genetics. General advantages of mouse models include: low maintenance cost, small size, …
Mouse models of obesity - PubMed
Animal models of obesity are also important for the development of future treatments of obesity. An agouti mouse mutation resulting in obese, yellow mice was described over a century ago …
Overview of Animal Models of Obesity - PMC - National Center for ...
The model has been used frequently in obesity research. The model has a historic perspective, e.g. because they enabled identification of major areas in the brain involved in the control of …
