The Mucorales is the largest and best-studied order of zygomycete fungi. Members of this order are sometimes called pin molds . The term mucormycosis is now preferred for infections caused by molds belonging to the order Mucorales.

Aug 25, 2023 · Mucormycosis is manifested by a variety of different syndromes in humans, particularly in immunocompromised patients and those with diabetes mellitus [1]. Devastating rhino-orbital-cerebral and pulmonary infections are the most common syndromes caused by …

Mucorales is a complex fungal group, including eleven different genera that can infect humans. This heterogeneity is associated with species-specific invasion pathways and responses to the host defense mechanisms.

Mucormycosis is a rare but severe fungal infection caused by mucormycete molds, which are found throughout the environment. Mucormycosis primarily affects people who are immunocompromised and those with uncontrolled diabetes. Clinical presentation depends on the body site affected.

Mucorales are significant fungal pathogens associated with high mortality, innate resistance to voriconazole, and variable susceptibility to the remaining mould-active triazoles.

Mucorales are thermotolerant moulds that are supposedly ubiquitous in nature and widely found on organic substrates, including bread, decaying fruits, vegetable matter, crop debris, soil between growing seasons, compost piles, and animal excreta.

Mucorales produce their uni-celled asexual spores (sporangiospores) endogenously, i.e., inside specialized cells. In contrast to the formation of conidia, cell walls of the sporangiospores are formed without the involvement of pre-existing cell walls.