Common side effects

• Nausea
• Diarrhea
• Headache disorder
• Anorexia
• Abdominal pain with cramps
• Alcohol intolerance
• Peripheral neuropathy
• Dysgeusia
• Vaginal dryness
• Xerostomia

If any of these effects persist or worsen, tell your doctor or pharmacist promptly

• Dizziness
• Headache
• Stomach upset
• Nausea
• Vomiting
• Loss of appetite
• Diarrhea
• Constipation
• Metallic taste in your mouth

Tell your doctor right away if you have any serious side effects, including

• Signs of a new infection
• Easy bruising/bleeding
• Stomach/abdominal pain
• Painful urination

Get medical help right away if you have any very serious side effects, including

• Unsteadiness
• Seizures
• Mental/mood changes
• Trouble speaking
• Numbness/tingling of arms/legs
• Eye pain
• Sudden vision changes
• Headache that is severe or doesn't go away
• Stiff/painful neck

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including

• Rash
• Itching/swelling
• Severe dizziness
• Trouble breathing

Other things to note

• This medication may cause your urine to turn darker in color. This effect is harmless and will disappear when the medication is stopped.
• Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

• Use sunscreen
• For gel with applicator products : Read instructions carefully. Insert into the vagina as directed. Avoid alcohol during therapy & 24 hrs after. Usually used at bedtime. Avoid alcohol in drinks, foods, and medicines. Refrain from intercourse during therapy. Call doctor if you are not better in 5 days.
• For lotion products : For external use only. Wash hands before and after using. Clean and dry skin, then use a thin layer on area. Keep away from eyes. Avoid sun lamps/prolonged direct sun. Call doctor if you are not better in 3 weeks. Ask doctor before use in other conditions. Follow directions on best place to keep drug supply.
• For suspension, oral products : Shake well before using. Measure dose using a dosing spoon/cup/syringe.
• For tablet products : If available, read the patient package insert. Avoid alcohol during and for 3 days after therapy. Take with food or milk to lessen stomach upset. Take with meals at evenly spaced intervals. May make you dizzy. Use caution when driving. Success is dependent on completing therapy course. May darken urine while taking this drug. Review all drugs you are taking with your doctor.

• Do not drink alcoholic beverages when using this medication. ; If this medication upsets your stomach, take it with crackers, bread or a small meal. ; May cause dizziness ; This drug may impair the ability to operate a vehicle, vessel (e.g., boat), or machinery. Use care until you become familiar with its effects. ; May cause discoloration of the urine or feces. ; Important: Finish all this medication unless otherwise directed by prescriber. ; For suspension, oral products : Shake well before using. ; For suspension, oral products : Store at room temperature. ; For suspension, oral products : Do not freeze ;

Before taking this medication, tell your doctor if you've had:

• Liver disease
• Kidney disease
• Certain blood disorders (low blood cell counts)

Products that may interact with this drug include:

• Alcohol-containing products (such as cough and cold syrups, aftershave)
• Products containing propylene glycol
• Lopinavir/ritonavir solution
• Lithium