MAPK/ERK pathway - Wikipedia
WEBThe MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
The MAPK cascades: Signaling components, nuclear roles and ...
WEBSep 1, 2011 · The MAPK cascades are central signaling pathways that regulate a wide variety of stimulated cellular processes, including proliferation, differentiation, apoptosis and stress response.
Function and Regulation in MAPK Signaling Pathways
WEBStudies of MAPK pathways in this organism continue to be especially informative in revealing the molecular mechanisms by which MAPK cascades operate, propagate signals, modulate cellular processes, and are controlled by regulatory factors both internal to and external to the pathways.
A Comprehensive Review on MAPK: A Promising Therapeutic ...
WEBOct 22, 2019 · The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch from extracellular signals to intracellular responses. Alterations of signaling cascades are found in various diseases, including cancer, as a result of genetic and epigenetic changes.
MAP Kinase Pathways - PMC - National Center for Biotechnology ...
WEBMAP kinases are activated within protein kinase cascades that regulate cell proliferation, differentiation, and death. In mammals, MAP kinases are grouped into three families: ERKs, JNKs, and p38/SAPKs.
Mammalian MAP kinase signalling cascades | Nature
WEBMar 1, 2001 · MAPKs are evolutionary conserved enzymes connecting cell-surface receptors to critical regulatory targets within cells. MAPKs also respond to chemical and physical stresses, thereby controlling...
Mitogen-activated protein kinase - Wikipedia
WEBA mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines.