Mar 7, 2024 · a leukocyte marker, known to be expressed on mature myeloid cells in the hematopoietic lineage, is expressed on a wide variety of tumor cells including myeloid leukemia, breast, colorectal, lung cancer cells.

Jul 30, 2018 · The most common leukemia biomarkers are CD (cluster of differentiation) markers, an extremely diverse series of membrane proteins predominantly expressed on the leukocyte surface. CD markers are mostly useful for classifying white blood cells (WBC) and especially important for the diagnosis of lymphomas and leukemias .

CD is an abbreviation “for cluster of differentiation”. CD molecules are cell surface markers which are very useful for the identification and characterization of leukocytes and the different subpopulations of leukocytes.

CD (cluster of diferentiation) molecules are cell surface markers useful for the identification and characterization of leukocytes. The CD nomenclature was developed and is maintained through the HLDA (Human Leukocyte Diferentiation Antigens) workshop started in 1982.

The cluster of differentiation (CD) is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell.

While CD molecules are very useful in defining leukocytes, they are not merely markers on the cell surface. Though only a fraction of known CD molecules have been thoroughly characterised, most of them have important functions.

CD markers for flow cytometry are used in many applications, including immunophenotyping (see below). The CD nomenclature has been developed and maintained by the HLDA (Human Leukocyte Differentiation Antigens) workshop.

Jul 1, 2013 · In acute leukemia, for example, some cases have distinctive features (like Auer rods) that tell you what kind of leukemia it is – but other cases have no clues. In cases where clues are minimal – particularly in hematolopoietic or lymphoid neoplasms – you can do flow cytometry to see what markers are on the surface of the cells.

CD markers, short for cluster of differentiation, are a system used to classify and identify specific molecules found on the surface of leukocytes, also known as white blood cells. Each CD marker is assigned a unique number, such as CD4 or CD8, allowing researchers and healthcare professionals to easily refer to them and understand their functions.

CD markers are leukocyte cell surface molecules, as well as the respective ligands expressed by other tissues. CD markers are used to identify, count, study, purify, destroy, or in some other way work with leukocytes.