Lamotrigine - StatPearls - NCBI Bookshelf
Feb 13, 2023 · This activity covers lamotrigine, including mechanism of action, pharmacology, adverse event profiles, eligible patient populations, contraindications, monitoring, and highlights the interprofessional team's role in managing lamotrigine therapy.
Lamotrigine: Uses, Interactions, Mechanism of Action - DrugBank …
Lamotrigine likely acts by inhibiting sodium currents by selective binding to the inactive sodium channel, suppressing the release of the excitatory amino acid, glutamate. The mechanism of action of lamotrigine in reducing anticonvulsant activity is …
Antiseizure medications: Mechanism of action, pharmacology ... - UpToDate
Jul 29, 2024 · While sharing a common property of suppressing seizures, antiseizure medications have many different pharmacologic profiles that are relevant when selecting and prescribing these agents in patients with epilepsy and other conditions.
Lamotrigine - Wikipedia
Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. [5][8] For epilepsy, this includes focal seizures, tonic-clonic seizures, and seizures in Lennox-Gastaut syndrome. [8]
LamoTRIgine: Dosage, Mechanism/Onset of Action, Half-Life
Feb 17, 2020 · Includes LamoTRIgine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Mood Stabilizers - StatPearls - NCBI Bookshelf
Apr 24, 2023 · Lamotrigine and carbamazepine are both capable of causing Stevens-Johnson syndrome; therefore, patients should learn to monitor themselves for any skin changes or new rashes after initiation of a mood stabilizer regimen with either of these drugs.
Mood Stabilizers: Lamotrigine | SpringerLink
Jan 10, 2020 · Lamotrigine (brand-name Lamictal, generic drugs available) is an anticonvulsant and mood stabilizing drug indicated for the treatment of epilepsy and for the prevention of depressive episodes in patients with bipolar I disorder …
Lamotrigine - PubMed
Feb 13, 2023 · Lamotrigine can be used to treat the following partial seizures, primary generalized tonic-clonic seizures, bipolar I disorder maintenance and Lennox-Gastaut syndrome. Off-label uses include treating acute bipolar depression, fibromyalgia, schizophrenia, and …
Antiepileptic drug cellular mechanisms of action: where does ...
Lamotrigine is effective against both partial and generalized seizures, including generalized absence seizures. Its sole documented cellular mechanism of action is sodium channel block, a mechanism shared by phenytoin and carbamazepine.
Lamotrigine - an overview | ScienceDirect Topics
Lamotrigine is an antiepileptic drug that is structurally unrelated to aromatic anticonvulsants. It acts on voltage-sensitive sodium channels, stabilizes neuronal membranes, and inhibits the release of excitatory neurotransmitter glutamate or aspartate.