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  1. Lambda phage - Wikipedia

    • Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny o… See more

    Anatomy

    The virus particle consists of a head and a tail that can have tail fibers. The whole particle consists of 12–14 … See more

    Life cycle

    Lambda phage is a non-contractile tailed phage, meaning during an infection event it cannot 'force' its DNA through a bacterial cell membrane. It must instead use an existing pathway to invade the host cell, having evol… See more

    Multiplicity reactivation and prophage reactivation

    Multiplicity reactivation (MR) is the process by which multiple viral genomes, each containing inactivating genome damage, interact within an infected cell to form a viable viral genome. MR was originally discovered … See more

    Repressor

    The repressor found in the phage lambda is a notable example of the level of control possible over gene expression by a very simple system. It forms a 'binary switch' with two genes under mutually exclusive expression… See more

    Lytic vs. lysogenic

    An important distinction here is that between the two decisions; lysogeny and lysis on infection, and continuing lysogeny or lysis from a prophage. The latter is determined solely by the activation of RecA in the SOS … See more

    As a genetic tool

    Lambda phage has been used heavily as a model organism and has been an excellent tool first in microbial genetics, and then later in molecular genetics. Some of its uses include its application as a vector for the cloning of … See more

     
  1. Studies of Lambda Phage Virus
  2. Lambdavirus - Wikipedia

  3. Phage Lambda: Morphology, Life Cycle and Genetic Map

  4. Bacteriophage Lambda Terminase and the Mechanism ...

    Bacteriophage λ is a temperate phage, which means that the virus may enter either of two infection pathways. The decision of which pathway to enter depends on the physiology of the host cell and the multiplicity of infection.

  5. Bacteriophage- Definition, Structure, Life Cycles, Applications, Phage

  6. From Bench to Keyboard and Back Again: A Brief History of …

  7. 7.14E: Bacteriophage Lambda as a Cloning Vector

  8. Structural mechanism of bacteriophage lambda tail's ... - Nature

  9. Bacteriophage lambda: Early pioneer and still relevant

  10. 9.7G: Temperate Bacteriophages - Lambda and P1 - Biology …