Kinesin - Wikipedia
WEBA kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme).
驱动蛋白 - 维基百科,自由的百科全书
WEB驱动蛋白(英語: Kinesin )是一类蛋白质超级家族,属于分子马达的一种,其成员代表驱动蛋白-1( Kinesin-1 )在1985年被发现。 驱动蛋白是由单体组成的多聚体,其“头部”具有 ATP酶 活性 [ 1 ] ,能通过水解 ATP 获得能量,改变构型,进行运动。
The functions of kinesin and kinesin-related proteins in eukaryotes
WEBAug 25, 2020 · Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks.
Kinesin superfamily motor proteins and intracellular transport
WEBKinesin superfamily proteins (also known as KIFs) are important molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs.
Traffic control: regulation of kinesin motors | Nature Reviews ...
WEBKinesins are a superfamily of molecular motors that generate force and/or motility along microtubule filaments. Kinesins contain a conserved motor domain for ATP hydrolysis and microtubule...
Kinesins at a glance - PMC - National Center for Biotechnology Information
WEBOct 10, 2010 · Kinesin was discovered in 1985 – 25 years ago – based on its motility in cytoplasm extruded from the giant axon of the squid (Allen et al., 1982; Brady et al., 1982; Vale et al., 1985). The purified protein, now known as kinesin-1, consisted of two heavy chains with motor activity that were associated with two light chains, which mediate ...
Kinesin: Fundamental Properties and Structure | SpringerLink
WEBIntroduction. Molecular motors, especially microtubule motors, play a critical role in the intracellular transport of membranous organelles, protein complexes, and mRNAs, and they also have a role in physiological processes such as brain wiring, higher brain function, neuronal survival, tumor suppression, and the determination of left-right ...
Kinesin Motor Enzymology: Chemistry, Structure, and Physics of ...
WEBFeb 13, 2015 · Most kinesins contain: (1) a catalytic domain (also known as a motor or head domain) responsible for nucleotide catalysis, microtubule binding, and force production, (2) a central α-helical stalk domain involved in coiled–coil interactions to organize the motor into higher order oligomers (e.g., dimers, tetramers), and (3) a tail domain ...
The mechanisms of kinesin motor motility: lessons from the
WEBBased on this structural information, we propose a common mechanism of kinesin motility, focusing on the regulation of kinesin motility through their interaction with microtubules and by their...
What is Kinesin? - News-Medical.net
WEBJul 19, 2023 · Kinesins are biological motor proteins that are ATP-dependent and function to assist cells with the transport of molecules along microtubules. Simply put, these proteins, function as highways...