IgG4-related disease - Wikipedia
IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.
Treatment and prognosis of IgG4-related disease - UpToDate
Mar 25, 2024 · The treatment and prognosis of IgG4-RD is presented here. The pathogenesis, clinical manifestations, diagnosis, and differential diagnosis of IgG4-RD are presented in detail separately, as is the treatment of type 1 AIP and IgG4-related sclerosing cholangitis.
IgG4-Related Disease - StatPearls - NCBI Bookshelf
Aug 8, 2023 · IgG4-related disease (IgG4-RD) is known as an IgG4-related systemic disease, hyper-IgG4 disease, IgG4-related autoimmune disease, IgG4-associated disease, IgG4-related sclerosing disease, and IgG4-syndrome.
Clinical manifestations and diagnosis of IgG4-related disease
Sep 10, 2024 · Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that is capable of affecting multiple organs [1-3]. Organs affected by IgG4-RD share pathologic, serologic, and clinical features.
IgG4-Related Disease: Diagnostic Criteria and Tests
Oct 2, 2024 · A newly recognized immune-mediated condition, immunoglobulin G4-related disease (IgG4-RD) is characterized by fibroinflammatory deposits in one or more organs. Although virtually any organ can be affected, IgG4-RD is seen most often in the lacrimal and salivary glands, thyroid gland, pancreas, eye orbits, paravertebral soft tissues, lungs, biliary system, kidneys, retroperitoneum, and meninges.
IgG4-Related Disease - IgG4-Related Disease - The Merck …
IgG4-related disease (IgG4-RD) is a chronic, immune-mediated disorder that often manifests with multiorgan involvement and tumor-like masses most often affecting the pancreas, bile ducts, lacrimal glands, orbital tissues, salivary glands, lungs, kidneys, retroperitoneal tissues, aorta, meninges, and thyroid gland.
Review: Diagnosis and management of IgG4-related disease
Oct 31, 2018 · IgG subclass 4-related disease (IgG4-RD) is a rare but increasingly recognised fibroinflammatory condition known to affect multiple organs. IgG4-RD is characterised by unique histological features of lymphoplasmacytic infiltration, storiform fibrosis and obliterative phlebitis.
IgG4-related disease: an update on pathophysiology and ...
Sep 16, 2020 · IgG4-related disease (IgG4-RD) is an insidiously progressive immune-mediated fibrotic disease typified by tumour-like mass formation in many affected organs.
IgG4-related disease: why is it so important? - PMC
Jun 30, 2018 · IgG4-related disease (IgG4-RD) is a recently defined systemic inflammatory and fibrous condition of unknown etiology and multiple clinical presentations. Characteristic features include elevated serum IgG4 levels in approximately 70% of patients; diffuse lymphoplasmocytic infiltrates rich in IgG4(+) cells; a “storiform” fibrosis pattern ...
IgG4-related disease—rare but you should not forget it
May 3, 2024 · Immunoglobulin G4-related disease (IgG4-RD) is a chronic fibroinflammatory disorder that was recognized in the 21st century and is characterized as a systemic and immune-mediated condition [1]. Other significant findings are …