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IFNG Gene - GeneCards | IFNG Protein | IFNG Antibody
WEBAug 6, 2024 · IFNG (Interferon Gamma) is a Protein Coding gene. Diseases associated with IFNG include Immunodeficiency 69 and Hepatitis C Virus. Among its related pathways are Antiviral mechanism by IFN-stimulated genes and Gene expression (Transcription).
IFNG-AS1 RNA Gene - GeneCards
WEBAug 6, 2024 · IFNG-AS1 (IFNG Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with IFNG-AS1 include Hashimoto Thyroiditis and Immune Thrombocytopenia. Among its related pathways is Extrafollicular and follicular B cell activation by SARS-CoV-2.
IFNγ: signalling, epigenetics and roles in immunity ... - Nature
WEBJun 19, 2018 · IFNγ is a cytokine that is primarily produced by cells of the immune system, including innate-like lymphocyte populations, such as natural killer (NK) cells and innate lymphoid cells (ILCs), and...
Targeting interferon-γ in hyperinflammation: opportunities and ...
WEBOct 5, 2021 · Interferon-γ (IFNγ) is a pleiotropic cytokine with multiple effects on the inflammatory response and on innate and adaptive immunity. Overproduction of IFNγ underlies several, potentially...
Interferon-γ: teammate or opponent in the tumour ... - Nature
WEBJun 21, 2021 · Interferon-γ (IFNγ) is a cytokine that has both protumour and antitumour activities, suggesting that it may serve as a nexus for responsiveness to immunotherapy. Many cancer...
Epithelial IFNγ signalling and compartmentalized antigen ... - Nature
WEBNov 22, 2023 · IBD increases the risk of developing colorectal cancer 45. To evaluate whether the epithelial antigen presentation pathway is relevant in colorectal cancer, we subjected IEC-specific IFNγR ...
Interferon-γ: an overview of signals, mechanisms and functions
WEBOct 2, 2003 · This article reviews the current understanding of IFN-γ ligand, receptor, ignal transduction, and cellular effects with a focus on macrophage responses and to a lesser extent, responses from other cell types that influence macrophage function during infection.
WEBIn 1983, a small protein and presumptive antiviral “interferon, IFN-g, was ” characterized as a factor released by antigen-stimulated lymphocytes that equips macro-phages to kill intracellular bacteria, protozoa, and fungi. Shortly thereafter, IFN-g became thefirst cytokineusedfor host-directed therapy of a nonviral infectious disease in humans.
Interferon-gamma (IFN-γ): Reviewing its mechanisms and …
WEBJun 1, 2023 · Interferon-gamma (IFN-γ) is a pleiotropic cytokine that plays a critical role in mediating an array of immune responses including promotes antiviral activity, facilitates macrophage activation, controls Th1/Th2 balance, …
Interferon Gamma - an overview | ScienceDirect Topics
WEBInterferon-gamma is a cytokine that plays regulatory roles in both the innate and adaptive immune systems. It is encoded by the IFNG gene and has been associated with protective effects against certain health conditions, such as BPD in infants. AI generated definition based on: Hematology, Immunology and Genetics (Third Edition), 2019
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