Holt–Oram syndrome (also called atrio-digital syndrome, atriodigital dysplasia, cardiac-limb syndrome, heart-hand syndrome type 1, HOS, ventriculo-radial syndrome) is an autosomal …

Feb 19, 2024 · What is Holt-Oram syndrome? Holt-Oram syndrome is a rare, congenital (present at birth) disorder. It often involves abnormal bones in your hands, wrists and arms, as well as …

Jul 20, 2004 · Holt-Oram syndrome (HOS) is characterized by upper-limb defects, congenital heart malformation, and cardiac conduction disease. Upper-limb malformations may be …

Holt-Oram syndrome is caused by genetic changes (pathogenic variantss) in the TBX5 gene. The syndrome is inherited in an autosomal dominant manner. A diagnosis of Holt-Oram syndrome …

Aug 14, 2023 · Holt-Oram syndrome also referred to as the heart-hand syndrome, is an autosomal dominant disorder that is characterized by upper limb abnormalities in association …

Holt-Oram syndrome is characterized by skeletal abnormalities of the hands and arms (upper limbs) and heart problems. Explore symptoms, inheritance, genetics of this condition.

May 7, 2020 · Holt-Oram syndrome is an autosomal dominant genetic condition that is associated with a change (mutation) in the TBX5 gene. While this mutation can be inherited, most cases …

Holt-Oram syndrome (HOS) prevalence is estimated at 1/ 100,000 live births (in Hungary), but various cases have been published worldwide. The clinical picture of HOS covers a wide …

Holt-Oram syndrome (HOS) is a rare monogenic disorder characterized by upper limb abnormalities, congenital heart defects and/or conduction abnormalities. It is determined by …

May 23, 2019 · Clinical characteristics: Holt-Oram syndrome (HOS) is characterized by upper-limb defects, congenital heart malformation, and cardiac conduction disease. Upper-limb …