Recent behavioral work suggests that long-term habituation in Aplysia critically involves postsynaptic processes, specifically, activation of AMPA- and NMDA-type receptors.
Long-term habituation of the gill-withdrawal reflex in
Nov 29, 2010 · To advance the goal of a comprehensive understanding of habituation, we have studied long-term habituation (LTH) of the gill-withdrawal reflex (GWR) in the marine snail Aplysia californica.
Habituation, Sensitization and Associative Learning in Aplysia
Because of the relative simplicity of its nervous system, the marine snail Aplysia has been useful for cellular studies of the mechanisms of nonassociative learning. We have found recently that this animal is also capable of associative learning.
5 - Habituation and Sensitisation in the Aplysia
Mar 22, 2018 · A developmental gene (Tolloid/BMP-1) is regulated in Aplysia neurons by treatments that induce long-term sensitization. Journal of Neuroscience , 17 ( 2 ), 755–64 . CrossRef Google Scholar PubMed
•Biology of Habituation: Why Sea Snails? Aplysia (invertebrates) are simple, with large unique neurons •Gill/siphon withdrawal reflex •Kandel’sAplysia research (e.g., Squire & Kandel, 1999) •Habituation of a gill withdrawal reflex •Repeated stimulation results in long-lasting (long-term memory?) habituation for several weeks.
Kandel’s breakthrough came through his pioneering work with Aplysia, which provided a wealth of information regarding non-associative learning and its forms (habituation and sensitization). neural circuits regulate behaviors.
Long-Term Habituation of a Defensive Withdrawal Reflex in Aplysia Abstract. A tcletile stimulus to the siphon of Aplysia produces a defensive withdrawal reflex consisting of contraction of the siphon, the gill, and the mantle shelf. We studied long-term hclbituation of this reflex using two types of prepara-
49 Molecular Mechanisms of Memory: Aplysia - pressbooks.pub
Shocking the tail following habituation activates a serotonergic neuron that facilitates glutamate release from from the siphon neuron, producing a strong gill withdrawal reflex. Over the long-term, this produces long lasting plasticity within this synapse.
Habituation in Aplysia: the Cheshire Cat of Neurobiology
Recent behavioral work suggests that long-term habituation in Aplysia critically involves AMPA receptor postsynaptic processes, specifically, activation of AMPA- and NMDA-type receptors.
The Neuronal Circuit for Simple Forms of Learning in Aplysia
Simple forms of learning (habituation, dishabituation, sensitization, and classical conditioning) of the Aplysia gill- and siphon-withdrawal reflex are due in part to plasticity of monosynaptic connections from sensory neurons to motor neurons.