Guanidinium | CH6N3+ | CID 32838 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Guanidinium chloride or guanidine hydrochloride, usually abbreviated GdmCl and sometimes GdnHCl or GuHCl, is the hydrochloride salt of guanidine.

Guanidine exists protonated, as guanidinium, in solution at physiological pH. Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins. Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfolding.

Guanidinium compounds are based on guanidine which is composed of three amino groups each bonded to the central carbon atom. From: Journal of Molecular Liquids, 2022

ChemSpider record containing structure, synonyms, properties, vendors and database links for guanidinium, ZRALSGWEFCBTJO-UHFFFAOYSA-O

Herein, we have systematically investigated the influence of guanidinium salts (GndSCN, GndNO 3, GndCl, Gnd 2 SO 4, and Gnd 2 CO 3) on polypeptide aggregation and hydrophobic collapse in aqueous solutions, focusing on the molecular mechanisms that give rise to protein solubility and stability. ELPs were employed as model biomacromolecules.

Guanidinium-rich scaffolds facilitate cellular translocation and delivery of bioactive cargos through biological barriers. Although impressive uptake has been demonstrated for nonoligomeric and nonpept(o)idic guanidinylated scaffolds in cell ...

The guanidinium functional group is commonly used by proteins and enzymes to recognize and bind anions using ion pairing and hydrogen bonding. The specific patterns of hydrogen bonding and the great basicity of the guanidine functional group allow it to play several...

3 days ago · Polycyclic nitrogen-rich energetic compounds have attracted the attention of domestic and foreign researchers due to their unique advantages in constructing low mechanical sensitivity, good thermal stability, and high-density new energetic molecules. In this study, a series of nitrogen-rich polycyclic energetic ion salts were synthesized. The resulting …

Guanidine Hydrochloride is a potent protein denaturant extensively utilized in the purification of proteins and nucleic acids. Widely recognized for its versatility, it plays a pivotal role in total RNA extraction experiments, dissolving proteins and disrupting …