Hemophilia C (Factor XI Deficiency): What It Is, Symptoms
WEBJun 20, 2022 — Hemophilia C (also known as Factor XI Deficiency or Rosenthal syndrome) is a rare form of hemophilia. Hemophilia is a blood disorder that happens when your blood doesn’t clot so your bleeding slows down or stops.
Factor XI - Wikipedia
WEBFactor XI, or plasma thromboplastin antecedent, is the zymogen form of factor XIa, one of the enzymes involved in coagulation. Like many other coagulation factors, it is a serine protease . In humans, factor XI is encoded by F11 gene .
Factor XI Deficiency: Causes, Diagnosis, and Treatment - Healthline
WEBJul 21, 2022 — Factor XI deficiency is a rare, inherited bleeding disorder. We discuss what it means to live with factor XI deficiency and what you can do about it.
Factor XI (eleven) deficiency - UpToDate
WEBAug 26, 2024 — Factor XI (eleven) is a plasma glycoprotein that acts in the contact phase of blood coagulation (the intrinsic pathway). Unlike the other contact factors (high molecular weight kininogen [HMWK], factor XII, and prekallikrein), factor XI is important for normal hemostasis in vivo.
Factor XI Deficiency | Symptoms, Genetics, Treatment | NBDF
WEBFactor XI (FXI) deficiency, also called hemophilia C, plasma thromboplastin antecedent deficiency and Rosenthal syndrome, was first recognized in 1953 in patients who experienced severe bleeding after dental extractions. Its incidence is estimated at 1 in 100,000 in the general population.
Structure and function of factor XI | Blood | American Society of ...
WEBApr 1, 2010 — Factor XI (FXI) is the zymogen of an enzyme (FXIa) that contributes to hemostasis by activating factor IX. Although bleeding associated with FXI deficiency is relatively mild, there has been resurgence of interest in FXI because of studies indicating it makes contributions to thrombosis and other processes associated with dysregulated …
Factor XI Deficiency - Symptoms, Causes, Treatment | NORD
WEBApr 27, 2022 — Factor XI deficiency is a rare genetic bleeding disorder caused by reduced levels and insufficient activity of a blood protein called factor XI. Factor XI is a clotting factor. Clotting factors are specialized proteins that are essential for proper clotting, the process by which blood solidifies like glue to plug the site of a wound to stop ...
Factor XI deficiency - MedlinePlus
WEBFactor XI deficiency is a disorder that can cause abnormal bleeding due to a shortage (deficiency) of the factor XI protein, which is involved in blood clotting. Explore symptoms, inheritance, genetics of this condition.
Biology of factor XI | Blood | American Society of Hematology
WEBApr 11, 2024 — Factor XI deficiency alters the cytokine response and activation of contact proteases during polymicrobial sepsis in mice.
Review Article: Structure and function of factor XI - PMC
WEBApr 1, 2010 — Factor XI (FXI) is the zymogen of an enzyme (FXIa) that contributes to hemostasis by activating factor IX. Although bleeding associated with FXI deficiency is relatively mild, there has been resurgence of interest in FXI because of studies indicating it makes contributions to thrombosis and other processes associated with dysregulated …