Sep 4, 2024 · What is eribulin? Eribulin is used to treat breast cancer that has spread to other parts of the body (metastatic). Eribulin is also used to treat liposarcoma, a rare type of cancer that develops in fatty tissue anywhere in the body. Eribulin is used for liposarcoma that cannot be treated with surgery, or has spread throughout the body.

Eribulin is a mechanistically unique inhibitor of microtubule dynamics, [25] [26] binding predominantly to a small number of high affinity sites at the plus ends of existing microtubules. [27] [28] Eribulin has both cytotoxic and non-cytotoxic mechanisms of action.

Eribulin mesylate is a type of chemotherapy drug called an antimicrotubule agent. It is a laboratory-made version of a natural product called halichondrin B. It works by disrupting microtubules (cellular structures that help move chromosomes during mitosis).

Who is HALAVEN ® (eribulin mesylate) Injection for? HALAVEN is a prescription medicine used to treat adults with breast cancer that has spread to other parts of the body, and who have already received other types of anticancer medicines after the cancer has spread.

Apr 5, 2015 · Eribulin mesylate (eribulin), an analogue of the marine natural product halichondrin B, is a microtubule-depolymerizing drug that has utility in the treatment of patients with breast cancer.

May 7, 2024 · Eribulin mesylate injection contains eribulin mesylate, a microtubule dynamics inhibitor. Eribulin mesylate is a synthetic analogue of halichondrin B, a product isolated from the marine sponge ...

Apr 21, 2018 · HALAVEN (eribulin mesylate) Injection is a non-taxane microtubule dynamics inhibitor. Eribulin mesylate is a synthetic analogue of halichondrin B, a product isolated from the marine sponge Halichondria okadai. HALAVEN is a clear, colorless, sterile solution for intravenous administration.

Eribulin mesylate is a manmade form of a product taken from a marine sponge. Eribulin mesylate works by disrupting how cancer cells divide. By altering how these cells divide, the cancer slows or stops growing.

Oct 31, 2011 · Eribulin mesylate, a nontaxane, completely synthetic microtubule inhibitor, has recently been approved by the U.S. Food and Drug Administration as third-line treatment of metastatic breast cancer refractory to anthracyclines and taxanes.

Apr 1, 2025 · Eribulin injection is used to treat metastatic (cancer that has already spread to other parts of the body) breast cancer in patients who have already received other types of cancer medicines.