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  1. Aprepitant
    AprepitantChemical compound
    GenericSide effectsWarningsInteractionsDosageCouponsIndicationsPrecautions
     

  2. Emend - Overview

    Generic name: aprepitant

    Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy).

    May Treat: Chemotherapy-induced nausea and vomiting · Post-operative nausea and vomiting

    Drug Class: Antiemetic - Substance P-Neurokinin 1 (NK1) Receptor Antagonists

    Availability: Prescription Required

    Pregnancy: Consult a doctor before using

    Lactation: Consult a doctor before using

    Alcohol: Limit intake while taking this medication

    Driving: May cause drowsiness or dizziness. Use caution

    Manufacturer: MERCK SHARP & D

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    Side effects

    Common side effects

    • Dehydration
    • Hypotension
    • Dyspepsia
    • Constipation
    • Dizziness
    • Fatigue
    • General weakness
    • Hiccups
    • Nausea
    • Diarrhea
    • Abdominal pain with cramps
    • Pruritus of skin
    • Eructation
    • Neutropenic disorder
    • Tinnitus
    • Gastritis
    • Leukopenia
    • Insomnia
    • Fever
    • Anorexia

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including

    • Rash
    • Itching/swelling
    • Severe dizziness
    • Trouble breathing

    Other things to note

    • Tiredness or hiccups may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly.

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    Precautions

    • If available, read the patient package insert
    • Tell doctor your complete medical history
    • Report to doctor any nausea or vomiting
    • Review all drugs you are taking with your doctor
    • May reduce effectiveness of hormone contraceptives
    • Room temperature
    • For capsule products : May take with or without food. Follow directions carefully. Protect from heat, light, & moisture.
    • For suspension, reconstituted, oral products : Store in the refrigerator Do not freeze.
    • For vial products : Drug is given by a nurse or a doctor. Inject into a vein, not into muscle/under skin. Refrigerate drug if not mixed by pharmacist.

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    Can emend be used with other medications?
    Emend is also used with other medications in adults and children 6 months of age and older to prevent delayed nausea and vomiting that may occur several days after receiving certain chemotherapy medications. Emend capsules are for use in adults and children who are at least 12 years old.
    drugs.com

    Warnings

    • This medication can interfere with the effectiveness of birth control pills. Consult your doctor or pharmacist.
    • For suspension, reconstituted, oral products : Keep in refrigerator. Do not freeze.

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    Interactions

    Before taking this medication, tell your doctor if you've had:

    • Liver disease

    Product interactions for this drug/drug-class include:

    • Daridorexant (>25 mg) with Moderate CYP3A4 Inhibitors (Contraindicated)
    • Lumateperone (>21 mg) with Moderate CYP3A4 Inhibitors (Contraindicated)
    • Mitapivat (> 20 mg) with Moderate CYP3A4 Inhibitors (Contraindicated)
    • Lonafarnib with Strong and Moderate CYP3A4 Inhibitors (Contraindicated)
    • Cilostazol (>50mg) with Slt Strong & Moderate CYP3A4 Inhibitors (Contraindicated)
    • Asunaprevir with Strong and Moderate CYP3A4 Inhibitors (Contraindicated)

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    Source: First Databank. For informational purposes only. Consult a medical professional for advice.
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    Table of Contents
    Overview
    Side effects
    Precautions
    Can emend be used with other medications?
    Warnings
    Ask an expert
    Interactions
     
  1. Drugs.com
    https://www.drugs.com › emend.html

    Emend: Uses, Dosage & Side Effects - Drugs.com

  2. Merck
    https://www.merck.com › ... › emend › emend_pi.pdf
    [PDF]

    HIGHLIGHTS OF PRESCRIBING INFORMATION EMEND …

  3. RxList
    https://www.rxlist.com › emend-drug.htm

    Emend Capsules (Aprepitant Capsules): Side Effects, …

    Jun 7, 2022 · Emend (aprepitant) is an antiemetic (anti-nausea) used together with other medications to prevent nausea and vomiting that may be caused by surgery or cancer chemotherapy. Emend is given ahead of time and will not …

  4. WebMD
    https://www.webmd.com › drugs

    Emend Oral: Uses, Side Effects, Interactions, Pictures

    Find patient medical information for Emend oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

  5. GoodRx
    https://www.goodrx.com › emend › what-is

    Emend (Aprepitant): Uses, Side Effects, Dosage & More - GoodRx

  6. Explore Emend Tab

  7. Merck
    https://www.merck.com › ... › emend › emend_ppi.pdf
    [PDF]

    Patient Information EMEND (EE mend) (aprepitant) capsules …

  8. Drugs.com
    https://www.drugs.com › pro › emend.h…

    Emend: Package Insert / Prescribing Information

    Jul 22, 2024 · Emend package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

  9. Drugs.com
    https://www.drugs.com › dosage › emend.html

    Emend Dosage Guide - Drugs.com

  10. MedBroadcast.com
    https://medbroadcast.com › drug › getdrug › emend

    Emend - Uses, Side Effects, Interactions - MedBroadcast.com

  11. Mayo Clinic
    https://www.mayoclinic.org › drugs-supplements › ...

    Aprepitant (oral route) - Mayo Clinic

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