EMT6 - CRL-2755 - ATCC
WEBEMT6 is a clonal isolate of EMT isolated in 1971 at Stanford University. The EMT6 cell line can be grown either in animals as a tumor or in tissue culture. Cells derived from tumors have a reported in vitro plating efficiency of 30%.
Acquired radioresistance in EMT6 mouse mammary carcinoma cell …
WEBFeb 22, 2023 · EMT6 RR_MJI (acquired radioresistance) cells was developed after 8 cycles of fractionated irradiation. The development of EMT6 RR_MJI cells was confirmed with further irradiation at different...
Primary tumor-induced immunity eradicates disseminated tumor …
WEBMar 29, 2019 · We show that despite their capacity to disseminate into secondary organs, 4T1 tumor models develop overt metastasis while EMT6-tumor bearing mice clear DTCs shed from primary tumors as well as...
Immunostimulatory and anti-tumor metronomic …
WEBJul 20, 2020 · We show that in orthotopic models of syngeneic murine triple-negative breast cancer (EMT6), CTX administered at 140 mg/kg every 6 days (CTX140 1q6d) is superior at inhibiting primary...
Tumor-immune profiling of murine syngeneic tumor models as a …
WEBNov 2, 2018 · As described above, EMT6 expresses the highest levels of MHC-I and chemokine genes, establishing it as the most immunogenic tumor cell line. Interestingly, PD-L1, IFNGR1, and elements of B cell function (for example BAFFR and BLNK) are overexpressed in RENCA relative to the other cell lines.
Cure of metastatic growth of EMT6 tumor cells in mice following ...
WEBOct 29, 2013 · In previous studies, we observed that regulation of expression of CD200, both on cells of a transplantable breast cancer, EMT6, and of the host, as well as of the receptor, CD200R in host mice, regulated local tumor growth and metastasis in immunocompetent animals.
Cellosaurus cell line EMT6 (CVCL_1923)
WEBResource Identification Initiative. To cite this cell line use: EMT6 (RRID:CVCL_1923) Comments. Characteristics: Established from the transplantable mammary tumour KHJJ. Derived from site: In situ; Mammary gland; UBERON= UBERON_0001911. Disease.
Acquired radioresistance in EMT6 mouse mammary carcinoma cell …
WEBFeb 22, 2023 · EMT6 RR_MJI (acquired radioresistance) cells was developed after 8 cycles of fractionated irradiation. The development of EMT6 RR_MJI cells was confirmed with further irradiation at different doses of gamma-ray, and both the survival fraction and migration rates were measured.
EMT-6 Tumor Model - Ichor Life Sciences
WEBThe EMT6 is a triple-negative mammary carcinoma with a less aggressive metastatic potential. EMT6 also expresses PD-L1, and adopts pulmonary metastasis readily upon implantation, making the EMT6 tumor model well suited …
Comparing syngeneic and autochthonous models of breast cancer …
WEBAug 5, 2021 · Immunophenotyping reveals differences in the tumor microenvironment in two versions of the EMT6 syngeneic breast cancer model. The EMT6 model of TNBC was employed as a second model to test how tumor cell …