Baclofen Uses, Dosage & Side Effects - Drugs.com
Sep 25, 2023 · Baclofen belongs to a class of medications called skeletal muscle relaxants. Baclofen is an antispasmodic agent that acts on spinal cord nerves and decreases the number and severity of muscle spasms in patients with certain conditions affecting the spinal cord.
Baclofen: MedlinePlus Drug Information
Baclofen is in a class of medications called skeletal muscle relaxants. Baclofen acts on the spinal cord nerves and decreases the number and severity of muscle spasms caused by multiple sclerosis or spinal cord conditions. It also relieves pain and improves muscle movement.
Baclofen - Wikipedia
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
Baclofen - StatPearls - NCBI Bookshelf
Aug 11, 2024 · Baclofen is a medication used to treat muscle spasticity, particularly in patients with conditions like spinal cord lesions and multiple sclerosis. Initially designed in 1960 to address epilepsy, baclofen was reintroduced in 1971 for its efficacy in treating muscle spasticity.
Baclofen Monograph for Professionals - Drugs.com
Jun 10, 2024 · Brand names: Gablofen, Lioresal Drug class: GABA-derivative Skeletal Muscle Relaxants. Medically reviewed by Drugs.com on Jun 10, 2024. Written by ASHP.
Baclofen: Uses, Interactions, Mechanism of Action | DrugBank ...
Baclofen is an agonist at the beta subunit of gamma-aminobutyric acid (GABA) receptors expressed on pre- and post-synaptic neurons. 3 Upon binding to GABA B receptors, baclofen causes an influx of potassium into the neuron, leading to hyperpolarization of the neuronal membrane and decreased calcium influx at presynaptic nerve terminals. This ...
Baclofen (oral route) - Mayo Clinic
Baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine.