DAPK1 - Wikipedia
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. [6]
Frontiers | Death Associated Protein Kinase 1 (DAPK1): A Regulator …
A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. J. Biol.
Death-associated protein kinase (DAPK) family modulators
Jun 27, 2020 · DAPK1 regulates apoptosis, autophagy, contributes to the pathogenesis of Alzheimer's disease, acts as a tumor suppressor, inhibits metastasis, mediates the body responses to viral infections, and regulates the synaptic plasticity and depression.
Tumor suppressor death-associated protein kinase 1 inhibits
May 4, 2020 · Death-associated protein kinase 1 (DAPK1, DAPk, DAPK) is known for its involvement in apoptosis and autophagy-associated cell death. Here, we identified an...
The death-associated protein kinases: structure, function, and …
Death-associated protein kinase (DAPk) is the founding member of a newly classified family of Ser/Thr kinases, whose members not only possess significant homology in their catalytic domains, but also share cell death-associated functions.
Death Associated Protein Kinase - an overview - ScienceDirect
Death-associated protein kinase (DAPK, also named DAPK-1) is a calcium/calmodulin-regulated serine/threonine kinase, which promotes either apoptosis or autophagic cell death in response to various stimuli, including oncogenes, detachment from extracellular matrix (ECM), activation of Fas/CD95 receptors, tumor necrosis factor-α (TNFα), and ...
Death-Associated Protein Kinase 1 Phosphorylation in Neuronal …
Jun 26, 2019 · Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin (Ca 2+ /CaM)-dependent serine/threonine (Ser/Thr) protein kinase that activates death signaling and regulates apoptotic neuronal cell death.
DAPK1 Gene - GeneCards | DAPK1 Protein | DAPK1 Antibody
Oct 1, 2024 · Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.
Death‐associated protein kinase (DAPK) family modulators: Current …
Jun 27, 2018 · DAPK1 regulates apoptosis, autophagy, contributes to the pathogenesis of Alzheimer's disease, acts as a tumor suppressor, inhibits metastasis, mediates the body responses to viral infections, and regulates the synaptic plasticity and depression.
1612 - Gene ResultDAPK1 death associated protein kinase 1
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.