Dabrafenib, sold under the brand name Tafinlar among others, is an anti-cancer medication used for the treatment of cancers associated with a mutated version of the gene BRAF. [2] …

Aug 12, 2024 · What is dabrafenib? Dabrafenib is used either alone or in combination with trametinib to treat certain types of cancer of the skin, lung, or thyroid. Dabrafenib is used in …

TAFINLAR is indicated, in combination with trametinib, for the adjuvant treatment of patients with melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test, and...

Dabrafenib is used alone or in combination with trametinib (Mekinist) to treat certain types of melanoma (a type of skin cancer). It is also used in combination with trametinib to prevent the …

Dabrafenib is used alone or in combination with trametinib to treat melanoma (skin cancer) that has spread or that cannot be removed by surgery. It is also used together with trametinib to …

Dabrafenib mesylate is approved to be used alone or with trametinib dimethyl sulfoxide to treat patients whose cancer has a certain mutation in the BRAF gene, including: Anaplastic thyroid …

Dabrafenib is used to treat various cancers (such as skin, thyroid, lung, solid tumors, brain). It belongs to a class of drugs known as kinase inhibitors. Dabrafenib works by slowing or...

Dabrafenib is 99.7% bound to human plasma proteins. The apparent volume of distribution (V c /F) is 70.3 L. Elimination. The mean terminal half-life is 8 hours. Hydroxy-dabrafenib terminal …

DABRAFENIB (da BRAF e nib) treats some types of cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

Nov 16, 2023 · Antineoplastic agent; an inhibitor of b-Raf serine-threonine kinase (BRAF) with V600E or V600K mutation. Used in combination with trametinib as adjuvant therapy following …