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  1. Wikipedia
    https://en.wikipedia.org/wiki/Dimethylformamide

    Dimethylformamide - Wikipedia

    • Dimethylformamide is an organic compound with the formula ( CH3)2N−C(=O)H. Commonly abbreviated as DMF (although this initialism is sometimes used for dimethylfuran, or dimethyl fu… See more

    Structure and Properties

    As for most amides, the spectroscopic evidence indicates partial double bond character for the C … See more

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    Reactions

    DMF is hydrolyzed by strong acids and bases, especially at elevated temperatures. With sodium hydroxide, DMF converts to formate and dimethylamine. DMF undergoes … See more

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    Production

    DMF was first prepared in 1893 by the French chemist Albert Verley (8 January 1867 – 27 November 1959), by distilling a mixture of dimethylamine hydrochloride and potassium f… See more

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    Applications

    The primary use of DMF is as a solvent with low evaporation rate. DMF is used in the production of acrylic fibers and plastics. It is also used as a solvent in peptide coupling fo… See more

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    Safety

    Reactions including the use of sodium hydride in DMF as a solvent are somewhat hazardous; exothermic decompositions have been reported at temperatures as low as 26 °C. O… See more

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    Is DMF a multipurpose reagent?
    Summary DMF is a commonly used solvent; its applications as a multipurpose reagent in numerous reactions have been discussed in this chapter, including amination, amidation, amidination, formylatio...
    onlinelibrary.wiley.com
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    Table of Contents
    Structure and Properties
    Reactions
    Production
    Applications
    Safety
    Is DMF a multipurpose reagent?
     
  1. Dimethylformamide
    • According to 2 sources
    N, N -Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation.

    N,N-Dimethylformamide …

    sigmaaldrich.com
    Dimethylformamide (DMF) is a polar aprotic solvent with a high boiling point (153 C). DMF is also used as a reagent in some reactions. A closely related solvent is dimethylacetamide (DMA).

    Dimethylformamide (DMF) …

    commonorganicchemistry.com
  2. People also ask
    What is DMF used for in organic synthesis?
    In one of its main uses in organic synthesis, DMF is a reagent in the Vilsmeier–Haack reaction, which is used to formylate aromatic compounds. The process involves initial conversion of DMF to a chloroiminium ion, [ (CH 3) 2 N=CH (Cl)] +, known as a Vilsmeier reagent, which attacks arenes.

    Dimethylformamide - Wikiwand

    wikiwand.com
    Is DMF a solvent?
    In the present review, we will reveal that DMF is actually something much more than a solvent. It is a unique chemical since, as well as being an effective polar aprotic solvent, it can play three other important roles in organic chemistry. It can be used as a reagent, a catalyst, and a stabilizer. Majid M. Heravi was born in 1952 in Mashhad, Iran.

    Beyond a solvent: triple roles of dimethylformamide in organic

    pubs.rsc.org
    Is DMF a multipurpose reagent?
    Summary DMF is a commonly used solvent; its applications as a multipurpose reagent in numerous reactions have been discussed in this chapter, including amination, amidation, amidination, formylatio...

    Applications of DMF as a Reagent in Organic Synthesis

    onlinelibrary.wiley.com
    Why is DMF a good polar solvent?
    Thus, it is especially useful in organic reactions when their mechanisms involve polar species, such as SN 2 reactions. 3 Therefore, DMF is mostly used as an excellent polar solvent with a relatively low evaporation rate, useful for a wide variety of organic transformations.

    Beyond a solvent: triple roles of dimethylformamide in organic

    pubs.rsc.org
    Does DMF have specific ion effects?
    DMF is miscible with water and the majority of organic solvents, as such it is used extensively as a solvent for chemical reactions. A summary of the trends in the strength of the specific-ion effects in DMF for a range of experiments is presented in Table 7.

    Dimethylformamide - an overview | ScienceDirect Topics

    sciencedirect.com
    Is DMF a reducing agent?
    According to literature results, DMF acts as a reducing agent for the reduction of Ag (I) to Ag (0). On this basis, DMF can act as a reducing agent for the transformation of W (VI) to W (IV) which in turn acts as a reducing agent for the conversion of Pd (II) to Pd (0) (Scheme 51). 136 Scheme 51 Conversion of W (VI) to W (IV) using DMF.

    Beyond a solvent: triple roles of dimethylformamide in organic

    pubs.rsc.org
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  3. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/product/sial/227056

    N,N-Dimethylformamide anhydrous, 99.8 68-12-2 - MilliporeSigma

  4. RSC Publishing
    https://pubs.rsc.org/en/content/articlehtml/2018/ra/c8ra04985h

    Beyond a solvent: triple roles of dimethylformamide in organic ...

  5. Common Organic Chemistry
    https://commonorganicchemistry.com/Common_Reagents/...

    Dimethylformamide (DMF) - Common Organic Chemistry

  6. Wikiwand
    https://www.wikiwand.com/en/articles/Dimethylformamide

    Dimethylformamide - Wikiwand

  7. Images of DMF Reagent

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  8. RSC Publishing
    https://pubs.rsc.org/en/content/articlepdf/2018/ra/c8ra04985h
    [PDF]

    Beyond a solvent: triple roles of dimethylformamide in …

  9. ScienceDirect
    https://www.sciencedirect.com/topics/chemical...

    Dimethylformamide - an overview | ScienceDirect Topics

  10. MilliporeSigma
    https://www.sigmaaldrich.com/IN/en/product/sigald/319937

    N,N-Dimethylformamide ACS reagent, = 99.8 68-12-2

  11. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/product/sial/437573

    N,N-Dimethylformamide ACS reagent, = 99.8 68-12-2

  12. Wiley Online Library
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/9783527831883.ch33

    Applications of DMF as a Reagent in Organic Synthesis