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  1. Wikipedia
    https://en.wikipedia.org/wiki/Cytisine

    Cytisine - Wikipedia

    • Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. It has been found effective in several randomized clinical trials, including in the United States and New Zealand, and is being inv… See more

    Other namesCytisine; Baptitoxine; Sophorine
    License dataDailyMed: Cytisine
    ATC codeN07BA04 (WHO)
    CAS Number485-35-8
    Sources

    Cytisine is extracted from the seeds of Cytisus laburnum L. (Golden Rain acacia), and is found in several genera of the subfamily Faboideae of the family Fabaceae, including Laburnum, Anagyris, Thermopsis, Cytisus… See more

    Uses

    Cytisine has been available in post-Soviet states for more than 40 years as an aid to smoking cessation under the brand name Tabex from the Bulgarian pharmaceutical company Sopharma AD. It was first marketed i… See more

    Cytisine versus Nicotine for Smoking Cessation | NEJM
    The New England Journal of Medicine
    Cytisine Uses, Benefits & Dosage - Drugs.com Herbal Database
    Drugs.com
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  1. Massachusetts General Hospital
    https://www.massgeneral.org/news/press-release/...

    First large U.S. clinical trial of cytisinicline finds the smoking ...

  3. The New England Journal of Medicine
    https://www.nejm.org/doi/full/10.1056/NEJ…

    Cytisine versus Nicotine for Smoking Cessation | NEJM

    Dec 18, 2014 · Cytisine is a plant-based alkaloid found in members of the Leguminosae family. 1,2 Like varenicline, cytisine is a partial agonist of nicotinic acetylcholine receptors (nAChRs), with an...

  4. Drugs.com
    https://www.drugs.com/npp/cytisine.html

    Cytisine Uses, Benefits & Dosage - Drugs.com Herbal Database

  5. JAMA Network
    https://jamanetwork.com/journals/jama/fullarticle/2807079

    Cytisinicline for Smoking Cessation - JAMA Network

  6. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S0376871623011742

    Cytisine for smoking cessation: A systematic review and meta …

  7. People also ask
    Does cytisine help stop smoking?
    Cytisine for nicotine addiction treatment. Addiction. 2019;114 (11):1951-1969. PubMed Google Scholar Crossref 5. Karnieg T, Wang X. Cytisine for smoking cessation. CMAJ. 2018;190 (19):E596. PubMed Google Scholar 6. Scharfenberg G, Benndorf S, Kempe G. Cytisine (Tabex) as a pharmaceutical aid in stopping smoking. Published in German.

    Effect of Cytisine vs Varenicline on Smoking Cessation

    jamanetwork.com
    What is cytisine used for?
    Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation.

    Cytisine - Wikipedia

    en.wikipedia.org
    Is cytisine an alkaloid?
    Cytisine is an alkaloid that exists naturally in the seeds of plants belonging to the Leguminosae/Fabaceae family, particularly L. anagyroides. Rouden 2014, Stead 2007 L. anagyroides, a small decorative garden tree (also called the Golden Rain Acacia due to its golden yellow flowers), is common in Central and Southern Europe.

    Cytisine Uses, Benefits & Dosage - Drugs.com Herbal Database

    drugs.com
    Where does cytisine come from?
    Cytisine is a naturally occurring alkaloid found in several plant species native to Central and Southern Europe, including Laburnum anagyroides or Cytisus laburnum (Prochaska et al., 2013). In the 1960s, cytisine was first studied in Eastern Europe and in the former Soviet Union for its potential as a smoking cessation aid.

    Cytisine for smoking cessation: A systematic review and meta-analysis

    sciencedirect.com
    When was cytisine first used?
    In the 1960s, cytisine was first studied in Eastern Europe and in the former Soviet Union for its potential as a smoking cessation aid. This led to the widespread use of cytisine as a smoking cessation aid in Eastern Europe and the Soviet Union.

    Cytisine for smoking cessation: A systematic review and meta-analysis

    sciencedirect.com
    Why is cytisinicline important?
    ImportanceCytisinicline (cytisine) is a plant-based alkaloid that, like varenicline, binds selectively to α4β2 nicotinic acetylcholine receptors, which mediate nicotine dependence.

    Cytisinicline for Smoking Cessation - JAMA Network

    jamanetwork.com
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  8. JAMA Network
    https://jamanetwork.com/journals/jama/f…

    Effect of Cytisine vs Varenicline on Smoking Cessation

    This study compares the effectiveness and safety of cytisine, a plant-derived nicotine receptor partial agonist, with varenicline, a prescription medication, for smoking cessation. The results show that cytisine is non …

  9. The BMJ
    https://www.bmj.com/content/347/bmj.f…

    Cytisine, the world’s oldest smoking cessation aid | The …

    Aug 23, 2013 · Cytisine is a plant-derived alkaloid that acts on nicotine receptors and helps people quit smoking. Learn about its history, mechanism, safety, and availability in this BMJ editorial.

  10. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC11129281

    Cytisine for smoking cessation: A 40-day treatment with an …

  11. PubChem
    https://pubchem.ncbi.nlm.nih.gov/compoun…

    Cytisine

    Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment …