Ceftolozane/tazobactam - Wikipedia
Ceftolozane/tazobactam, sold under the brand name Zerbaxa, (Merck) is a fixed-dose combination antibiotic medication used for the treatment of complicated urinary tract infections and complicated intra-abdominal infections in adults.
ceftolozane/tazobactam (Rx) - Medscape Drugs & Diseases
Indicated for complicated urinary tract infections (cUTI), including pyelonephritis, caused by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa....
Ceftolozane and tazobactam (intravenous route) - Mayo Clinic
Ceftolozane and tazobactam combination is an antibiotic that belongs to the group of medicines known as cephalosporins and beta-lactamase inhibitors. It works by killing bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
Ceftolozane and tazobactam Uses, Side Effects & Warnings - Drugs.com
Jun 4, 2024 · What is ceftolozane and tazobactam? Ceftolozane and tazobactam is a combination antibiotic that is used to treat certain bacterial infections of the lungs, stomach, or urinary tract. Ceftolozane and tazobactam is sometimes given in combination with another antibiotic medicine.
Ceftolozane/Tazobactam: A New Option in the Treatment of …
Ceftolozane/tazobactam also demonstrated superior in vitro activity against ceftazidime-resistant Escherichia coli and K. pneumoniae when compared with ceftriaxone, cefepime, and piperacillin/tazobactam.
Dosing for ZERBAXA® (ceftolozane and tazobactam)
ZERBAXA® (ceftolozane and tazobactam) is indicated for the treatment of adult patients (18 years and older) with hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by the following susceptible Gram-negative microorganisms: Enterobacter cloacae, Escherichia coli, Haemophilus influenzae ...
Ceftolozane/Tazobactam Monograph for Professionals - Drugs.com
Aug 25, 2023 · Ceftolozane and tazobactam is a fixed combination of ceftolozane (a fifth generation cephalosporin) and tazobactam (a β-lactamase inhibitor). Like other cephalosporins, antibacterial activity of ceftolozane results from inhibition of mucopeptide synthesis in bacterial cell wall and is mediated by penicillin-binding proteins (PBPs).
Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase …
Ceftolozane is a novel cephalosporin currently being developed with the β-lactamase inhibitor tazobactam for the treatment of complicated urinary tract infections (cUTIs), complicated intra-abdominal infections (cIAIs), and ventilator-associated bacterial pneumonia (VABP).
Ceftolozane-tazobactam: A new-generation cephalosporin
Dec 15, 2015 · Summary: Ceftolozane-tazobactam (Zerbaxa, Cubist Pharmaceuticals) is a cephalosporin β-lactam and β-lactamase inhibitor marketed as a fixed-dose combination agent for the treatment of complicated urinary tract and intraabdominal infections.
Ceftolozane and Tazobactam Injection - MedlinePlus
The combination of ceftolozane and tazobactam is used to treat certain infections including urinary tract infections and infections of the abdomen (stomach area). It is also used to treat certain types of pneumonia that developed in people …